Tag: Comparative Genomics Resource (CGR)

Improved Gene Data Access with Redesigned NCBI Gene Pages

Improved Gene Data Access with Redesigned NCBI Gene Pages

We are excited to announce redesigned NCBI Gene pages. The redesigned pages (available through NCBI Datasets) offer a modern, clean interface with an intuitive layout that makes browsing and downloading NCBI Gene data easier. The legacy Gene page will continue to be available during this transition period, and we will continue to communicate updates and changes through NCBI websites and this blog.    VSports app下载.

What’s new? 
  • Improved Search Capabilities: The new Gene landing page offers improved search functionality, allowing users to find gene information more effectively. Users can now search by taxon, locus tag and symbol (with or without specifying a taxon, and above species level) in addition to NCBI GeneID and accession. 

Continue reading “Improved Gene Data Access with Redesigned NCBI Gene Pages”

Compare Nucleotide Differences in the Multiple Comparative Genome Viewer (MCGV)!

Compare Nucleotide Differences in the Multiple Comparative Genome Viewer (MCGV)! (VSports注册入口)

NCBI’s new Multiple Comparative Genome Viewer (MCGV) is an interactive graphical genome browser that allows you to visualize multiple genome assemblies in a single view. MCGV displays whole genome alignments created by the research community.   VSports手机版.

What’s new?

We made several significant updates to this application since its initial release last winter V体育安卓版. Now you can:  .

  • View gene annotation with exon and intron structure for all assemblies 
  • Filter your view to only the assemblies and species you want to compare 
  • Change the alignment dataset to view an 8-way ape alignment with the choice of multiple alternate anchor assemblies 

Continue reading “Compare Nucleotide Differences in the Multiple Comparative Genome Viewer (MCGV). ” → V体育ios版.

Faster, Better Results for Protein BLAST Searches

Faster, Better Results for Protein BLAST Searches (VSports最新版本)

Effective August 2025, ClusteredNR will become the protein BLAST default database 

We are excited to announce that the default database for protein BLAST searches will soon be the NCBI ClusteredNR database. Introduced in 2022, ClusteredNR is a collection of protein sequence clusters built from the current default database, nr VSports最新版本. The representative sequence is chosen for each cluster, which is generally well-annotated and indicates the function of the proteins in the cluster, helping you focus on meaningful biological insights and decreasing redundant results.  .

What’s better about ClusteredNR?
  • Faster searches 
  • Decreased redundancy in results 
  • Broader taxonomic coverage in results 

Continue reading “Faster, Better Results for Protein BLAST Searches”

RefSeq Release 229 is Now Available!

RefSeq Release 229 is Now Available!

Check out RefSeq release 229, now available online and from the FTP site. You can access RefSeq data through NCBI Datasets VSports注册入口. The release is provided in several directories as a complete dataset and also as divided by logical groupings.

What’s included in this release?

As of March 3, 2025, this full release incorporates genomic, transcript, and protein data containing:

  • 522,879,448 records
  • 399,577,538 proteins
  • 68,985,910 RNAs
  • Sequences from 164,117 organisms 

Continue reading “RefSeq Release 229 is Now Available. ” → VSports在线直播.

New! Introducing the Multiple Comparative Genome Viewer (MCGV) Beta Release

"V体育2025版" New! Introducing the Multiple Comparative Genome Viewer (MCGV) Beta Release

NLM’s NCBI is excited to introduce the Multiple Comparative Genome Viewer (MCGV), a new tool in active development that allows you to visualize an alignment of multiple eukaryotic genomes. While our existing Comparative Genome Viewer (CGV) allows you to compare pairs of eukaryotic assemblies, the new MCGV tool can help you analyze multiple assemblies in a single view V体育2025版.   .

MCGV displays are based on multiple whole genome sequence alignments. You can navigate these alignments in the viewer to track evolutionarily related regions across strains or species VSports. Focus in on a particular genome region to investigate how differences in genome structure may have contributed to differences in gene sequence and function. You can access MCGV by clicking on the “Visualize gene across species” link via the gene search results page.    Continue reading “New. Introducing the Multiple Comparative Genome Viewer (MCGV) Beta Release” →.

NCBI Resources Highlighted in 2025 Nucleic Acids Research Database Issue

NCBI Resources Highlighted in 2025 Nucleic Acids Research Database Issue

The 2025 Nucleic Acids Research Database Issue features papers from NCBI staff on ClinVar, PubChem, GenBank, RefSeq, and more. The citations are available in PubMed with full-text available in PubMed Central (PMC). To read an article, click on the PMCID number listed below. 

Database resources of the National Center for Biotechnology Information in 2025

PMCID: PMC11701734

NCBI provides online information resources for biology, including the GenBank® nucleic acid sequence repository and the PubMed® repository of citations and abstracts published in life science journals. NCBI is currently developing the NIH Comparative Genomics Resource (CGR) to facilitate reliable comparative genomics analyses with an NCBI Toolkit and community collaboration.

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RefSeq Release 228 is Available!

RefSeq Release 228 is Available!

Check out RefSeq release 228, now available online and from the FTP site. You can access RefSeq data through NCBI Datasets. The release is provided in several directories as a complete dataset and also as divided by logical groupings.

What’s included in this release?

As of January 3, 2025, this full release incorporates genomic, transcript, and protein data containing:

  • 513,096,240 records, including
  • 391,903,900 proteins
  • 67,997,702 RNAs
  • Sequences from 162,138 organisms 

Continue reading “RefSeq Release 228 is Available!”

Try Out a Development Version of NCBI’s Publicly Available Annotation Tool, EGAPx

Try Out a Development Version of NCBI’s Publicly Available Annotation Tool, EGAPx

Latest release now available 

Are you generating genomes for vertebrates, arthropods, or plants, and looking for a way to generate high-quality genome annotation? NCBI is working on a public version of the NCBI Eukaryotic Genome Annotation Pipeline (EGAPx), and the latest developmental release is now available for testing and feedback. Continue reading “Try Out a Development Version of NCBI’s Publicly Available Annotation Tool, EGAPx”

RefSeq Release 227 is Available!

RefSeq Release 227 is Available!

Check out RefSeq release 227, now available online and from the FTP site. You can access RefSeq data through NCBI Datasets. The release is provided in several directories as a complete dataset and also as divided by logical groupings.

What’s included in this release?

As of November 4, 2024, this full release incorporates genomic, transcript, and protein data containing:

  • 497,549,107 records, including
  • 377,783,847 proteins
  • 66,987,567 RNAs
  • Sequences from 159,324 organisms 

Continue reading “RefSeq Release 227 is Available!”

Expansion of Ortholog Data for RefSeq Arthropods

VSports最新版本 - Expansion of Ortholog Data for RefSeq Arthropods

250K+ new Hymenoptera orthologs added 

NCBI is excited to announce the expansion of ortholog data for RefSeq arthropods. This update expands the breadth of arthropod orthology information, offering new insights into evolutionary biology, gene function, and shared pathways. Whether you’re studying insect genetics, developmental biology, or comparative genomics, the expanded ortholog data opens up new possibilities for research. Check out our previous blog to learn how to access the orthologs using NCBI Datasets.  Continue reading “Expansion of Ortholog Data for RefSeq Arthropods”