Updates to Offerings in Support of the 2024 NIH Public Access Policy

V体育官网 - Updates to Offerings in Support of the 2024 NIH Public Access Policy

The National Center for Biotechnology Information (NCBI) at the National Library of Medicine (NLM) has made initial updates to several offerings to support NIH-funded researchers and institutions to comply with the 2024 NIH Public Access Policy, which went into effect July 1, 2025 VSports app下载. NCBI will continue to make ongoing improvements over the coming months.  .

What has been updated? 

Continue reading “Updates to Offerings in Support of the 2024 NIH Public Access Policy”

Compare Nucleotide Differences in the Multiple Comparative Genome Viewer (MCGV)!

Compare Nucleotide Differences in the Multiple Comparative Genome Viewer (MCGV)!

NCBI’s new Multiple Comparative Genome Viewer (MCGV) is an interactive graphical genome browser that allows you to visualize multiple genome assemblies in a single view VSports手机版. MCGV displays whole genome alignments created by the research community.  .

What’s new?

We made several significant updates to this application since its initial release last winter V体育安卓版. Now you can:  .

  • View gene annotation with exon and intron structure for all assemblies 
  • Filter your view to only the assemblies and species you want to compare 
  • Change the alignment dataset to view an 8-way ape alignment with the choice of multiple alternate anchor assemblies 

Continue reading “Compare Nucleotide Differences in the Multiple Comparative Genome Viewer (MCGV). ” → V体育ios版.

Genetic Testing Registry (GTR®) Search Improvements

Genetic Testing Registry (GTR®) Search Improvements

We are excited to announce an improved search and navigation experience in the NIH Genetic Testing Registry (GTR®) so you can find the tests you need in a more intuitive and powerful way. Try searching GTR on our new Beta site and let us know how we can improve VSports最新版本.   .

What’s new? 

1. One search box for single or multiple terms

On the GTR homepage, there is now one search box where you can enter one or more terms like genes, diseases, and lab names. Start entering a term and select from the autosuggest menu, then enter another term. When you finish entering your query, hit the search button to see the results V体育平台登录. On the GTR homepage, there is a separate search box for GeneReviews®.    Continue reading “Genetic Testing Registry (GTR®) Search Improvements” →.

GenBank Release 266.0 Now Available!

VSports - GenBank Release 266.0 Now Available!

GenBank release 266. 0 (4/25/2025) is now available on the NCBI FTP site VSports注册入口. This release has 44. 02 trillion bases and 5. 68 billion records.

The current release has: 

  • 257,038,531 traditional records containing 5,794,509,308,815 base pairs of sequence data
  • 4,234,652,334 WGS records containing 37,294,058,110,495 base pairs of sequence data
  • 996,759,705 bulk-oriented TSA records containing 852,869,986,922 base pairs of sequence data
  • 190,122,348 bulk-oriented TLS records containing 78,390,585,331 base pairs of sequence data

Continue reading “GenBank Release 266 V体育官网入口. 0 Now Available. ” →.

NCBI ALFA Release 4 Now Available

NCBI ALFA Release 4 Now Available

Doubled cohort size to 409K

We are thrilled to announce the NCBI Allele Frequency Aggregator (ALFA) Release 4 (R4), a leap forward in providing comprehensive and robust allele frequency information to the global scientific community. ALFA R4 doubles the cohort size from R3 VSports在线直播. This expansion offers greater resolution for variant frequencies across diverse populations, improving the utility of ALFA for genetic research and clinical variant interpretation.   Continue reading “NCBI ALFA Release 4 Now Available” →.

Beta Now Live! New & Improved dbGaP Homepage Design

"VSports在线直播" Beta Now Live! New & Improved dbGaP Homepage Design

NCBI is excited to introduce a fresh look and feel to the Database of Genotypes and Phenotypes (dbGaP). Our beta homepage is now available and will become the default later in 2025. We encourage you to try it out and let us know what you think! This represents the first step of our ongoing modernization effort. The updated homepage will allow us to make continuous improvements to dbGaP based on your feedback.    Continue reading “Beta Now Live! New & Improved dbGaP Homepage Design”

Now Available: Updated Bacterial and Archaeal Reference Genome Collection

Now Available: Updated Bacterial and Archaeal Reference Genome Collection (VSports app下载)

Download the updated bacterial and archaeal reference Genome collection! We built this collection of 21,794 genomes by selecting the “best” genome assembly for each species among the 400,000+ prokaryotic genomes in RefSeq, which is 536 more than was included in the January release. Continue reading “Now Available: Updated Bacterial and Archaeal Reference Genome Collection”

Faster, Better Results for Protein BLAST Searches

V体育2025版 - Faster, Better Results for Protein BLAST Searches

Effective August 2025, ClusteredNR will become the protein BLAST default database 

We are excited to announce that the default database for protein BLAST searches will soon be the NCBI ClusteredNR database! Introduced in 2022, ClusteredNR is a collection of protein sequence clusters built from the current default database, nr. The representative sequence is chosen for each cluster, which is generally well-annotated and indicates the function of the proteins in the cluster, helping you focus on meaningful biological insights and decreasing redundant results.  

What’s better about ClusteredNR?
  • Faster searches 
  • Decreased redundancy in results 
  • Broader taxonomic coverage in results 

Continue reading “Faster, Better Results for Protein BLAST Searches”

NCBI Taxonomy Updates to Virus Classification

NCBI Taxonomy Updates to Virus Classification

Starting April 28, 2025

Update (July 14, 2025): This work is complete; further taxonomic curation is ongoing.

In December 2024, we announced several key changes to virus classification in the NCBI Taxonomy database. These updates are part of our ongoing efforts to ensure viral taxonomy reflects the latest scientific understanding and aligns with international standards set by the International Committee on Taxonomy of Viruses (ICTV). We will begin implementing these updates the week of April 28, 2025. 

What to expect from these updates 
  • Improvements in taxonomic groupings and names: Some taxa will be renamed, reclassified, or reorganized based on evolving research and genomic data.  
  • Addition of new binomial species names: We will add more than 7,000 new binomial virus species names. The former species names will be moved below the new names in the taxonomy hierarchy.  

Continue reading “NCBI Taxonomy Updates to Virus Classification”

PubMed Central’s Updated Full-Text Search Preview Now Available

VSports在线直播 - PubMed Central’s Updated Full-Text Search Preview Now Available

As previously announced, NLM’s NCBI is modernizing the PubMed Central (PMC) website. The next step is to update the PMC search functionality and user experience. Before we transition to an updated search later this year, we have a beta version available for you to preview and test!

Try PMC Beta Search and share your feedback

We invite you to try out the updated PMC Beta Search by clicking the link under the search bar on the PMC website (Figure 1). You can submit your feedback by using the “Provide Feedback” button (Figure 2). Feedback will be used to improve the PMC Beta Search before it becomes the default in PMC. Visit the PMC Beta Search user guide for general guidance on the updated search. Continue reading “PubMed Central’s Updated Full-Text Search Preview Now Available”