Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The . gov means it’s official. Federal government websites often end in . gov or . mil VSports app下载. Before sharing sensitive information, make sure you’re on a federal government site. .

Https

The site is secure V体育官网. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely. .

Multicenter Study
. 2025 Sep 8;9(5):zraf094.
doi: 10.1093/bjsopen/zraf094.

Breast satisfaction and health-related quality of life following total mastectomy, breast-conserving surgery, or immediate breast reconstruction in Japanese patients with breast cancer: multicentre cross-sectional controlled study (Reborn) (V体育平台登录)

Hirohito Seki  1 , Takako Komiya  2 , Yoshihiro Sowa  3 , Maho Kato  4   5 , Yutaka Nishida  6 , Hirotsugu Isaka  1 , Jyunji Takano  7 , Shigeru Imoto  1 , Miho Saiga  8
Affiliations
Multicenter Study

"VSports app下载" Breast satisfaction and health-related quality of life following total mastectomy, breast-conserving surgery, or immediate breast reconstruction in Japanese patients with breast cancer: multicentre cross-sectional controlled study (Reborn)

Hirohito Seki et al. BJS Open. .

Abstract

Background: Surgical decision-making for breast cancer requires consideration of both treatment outcomes and health-related quality of life (HR-QoL). However, data on HR-QoL differences across surgical procedures remain limited. This study compared breast satisfaction and HR-QoL among Japanese patients with breast cancer undergoing mastectomy (MT), breast-conserving surgery (BCS), or immediate breast reconstruction (IBR). VSports手机版.

Methods: A survey using the Japanese version of the BREAST-Q was conducted among patients with primary breast cancer who underwent surgery between August 2013 and July 2021. V体育安卓版.

Results: Of 648 patients, 577 were included in this study. The median time from surgery to questionnaire completion was 56 months. Satisfaction with breast scores was highest in patients undergoing BCS, followed by those undergoing IBR and MT. Psychosocial and sexual well-being were significantly better in patients undergoing BCS and IBR than in those undergoing MT, whereas physical well-being showed no significant differences among the three groups. In multiple regression analysis, surgical procedure was identified as the most influential factor for breast satisfaction, psychosocial well-being, and sexual well-being. V体育ios版.

Conclusions: This multicentre Japanese study confirmed that the choice of surgical procedure is the most influential factor affecting postoperative HR-QoL, with both BCS and IBR offering advantages over MT. The findings highlight the importance of comprehensive preoperative counselling to ensure patients receive detailed information on potential HR-QoL differences. VSports最新版本.

Keywords: BREAST-Q; patent-reported outcome; physical well-being; psychosocial well-being; satisfaction with breasts. V体育平台登录.

PubMed Disclaimer

Figures

Fig. 1
Fig. 1
Flow chart showing patient recruitment The survey response rate was 90.2% (577 of 640).
Fig. 2
Fig. 2
Scores for different domains on the BREAST-Q in all patients and according to type of procedure a Satisfaction with breasts. b Physical well-being (chest). c Psychosocial well-being. d Sexual well-being. Symbols show mean values, with error bars indicating 95% confidence intervals. MT, total mastectomy; BCS, breast-conserving surgery; IBR, immediate breast reconstruction.
See this image and copyright information in PMC

References (V体育2025版)

    1. Fisher B, Anderson S, Redmond CK, Wolmark N, Wickerham DL, Cronin WM. Reanalysis and results after 12 years of follow-up in a randomized clinical trial comparing total mastectomy with lumpectomy with or without irradiation in the treatment of breast cancer. N Engl J Med 1995;333:1456–1461 - PubMed
    1. Arriagada R, Le MG, Rochard F, Contesso G. Conservative treatment versus mastectomy in early breast cancer: patterns of failure with 15 years of follow-up data. Institute Gustave-Roussy Breast Cancer Group. J Clin Oncol 1996;14:1558–1564 - PubMed
    1. Katipamula R, Degnim AC, Hoskin T, Boughey JC, Loprinzi C, Grant CS et al. Trends in mastectomy rates at the Mayo Clinic Rochester: effect of surgical year and preoperative magnetic resonance imaging. J Clin Oncol 2009;27:4082–4088 - PMC - PubMed
    1. Mohamedahmed AYY, Zaman S, Zafar S, Laroiya I, Iqbal J, Tan MLH et al. Comparison of surgical and oncological outcomes between oncoplastic breast-conserving surgery versus conventional breast-conserving surgery for treatment of breast cancer: a systematic review and meta-analysis of 31 studies. Surg Oncol 2022;42:101779. - PubMed
    1. Vasilyeva E, Nichol A, Bakos B, Barton A, Goecke M, Lam E et al. Breast conserving surgery combined with radiation therapy offers improved survival over mastectomy in early-stage breast cancer. Am J Surg 2024;231:70–73 - PubMed

MeSH terms