Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The . gov means it’s official. Federal government websites often end in . gov or . mil. Before sharing sensitive information, make sure you’re on a federal government site. VSports app下载.

Https

The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely. V体育官网.

Comparative Study
. 2017 Jan 5;7(1):e013925.
doi: 10.1136/bmjopen-2016-013925.

Measuring shear-wave speed with point shear-wave elastography and MR elastography: a phantom study

Affiliations
Comparative Study

Measuring shear-wave speed with point shear-wave elastography and MR elastography: a phantom study

Riwa Kishimoto et al. BMJ Open. .

Abstract

Objectives: To compare shear-wave speed (SWS) measured by ultrasound-based point shear-wave elastography (pSWE) and MR elastography (MRE) on phantoms with a known shear modulus, and to assess method validity and variability VSports手机版. .

Methods: 5 homogeneous phantoms of different stiffnesses were made. Shear modulus was measured by a rheometer, and this value was used as the standard. 10 SWS measurements were obtained at 4 different depths with 1. 0-4. 5 MHz convex (4C1) and 4. 0-9. 0 MHz linear (9L4) transducers using pSWE. MRE was carried out once per phantom, and SWSs at 5 different depths were obtained V体育安卓版. These SWSs were then compared with those from a rheometer using linear regression analyses. .

Results: SWSs obtained with both pSWE as well as MRE had a strong correlation with those obtained by a rheometer (R2>0. 97). The relative difference in SWS between the procedures was from -25. 2% to 25. 6% for all phantoms, and from -8. 1% to 6. 9% when the softest and hardest phantoms were excluded. Depth dependency was noted in the 9L4 transducer of pSWE and MRE V体育ios版. .

Conclusions: SWSs from pSWE and MRE showed a good correlation with a rheometer-determined SWS. Although based on phantom studies, SWSs obtained with these methods are not always equivalent, the measurement can be thought of as reliable and these SWSs were reasonably close to each other for the middle range of stiffness within the measurable range. VSports最新版本.

Keywords: acoustic radiation force impulse; elastography; rheometer; shear wave V体育平台登录. .

PubMed Disclaimer

Conflict of interest statement (V体育官网)

Conflicts of Interest: None declared.

Figures

Figure 1
Figure 1
Velocity map with MRE of a phantom of SWS=2.23 m/s (storage modulus=5.2 kPa). ROI was set at 2.0, 3.0, 4.0, 5.0 and 6.0 cm depth. Depth dependence of SWS is demonstrated.MRE, MR elastography; ROI, region of interest; SWS, shear-wave speed.
Figure 2
Figure 2
SWS at a 4 cm depth measured with pSWE (4C1 and 9L4 transducer) and MRE compared with that of a rheometer. MRE,MR elastography; pSWE, point shear-wave elastography; SWS, shear-wave speed.
Figure 3
Figure 3
Depth dependency of SWS with pSWE (4C1 and 9L4 transducer) and MRE at each depth. The SWS ratio is calculated by dividing each SWS by a rheometer-determined SWS. Significant differences between depths were found for pSWE (9L4) and for MRE with one-way ANOVA.ANOVA, analysis of variance; MRE, MR elastography; pSWE, point shear-wave elastography; SWS, shear-wave speed.

References

    1. Goertz RS, Amann K, Heide R et al. . An abdominal and thyroid status with acoustic radiation force impulse elastometry—a feasibility study: acoustic radiation force impulse elastometry of human organs Eur J Radiol 2011;80:e226–30. 10.1016/j.ejrad.2010.09.025 - DOI - PubMed
    1. Tozaki M, Isobe S, Fukuma E. Preliminary study of ultrasonographic tissue quantification of the breast using the acoustic radiation force impulse (ARFI) technology. Eur J Radiol 2011;80:e182–7. 10.1016/j.ejrad.2011.05.020 - DOI - PubMed
    1. Friedrich-Rust M, Wunder K, Kriener S et al. . Liver fibrosis in viral hepatitis: noninvasive assessment with acoustic radiation force impulse imaging versus transient elastography. Radiology 2009;252:595–604. 10.1148/radiol.2523081928 - DOI (V体育官网入口) - PubMed
    1. Ichikawa S, Motosugi U, Morisaka H et al. . Validity and reliability of magnetic resonance elastography for staging hepatic fibrosis in patients with chronic hepatitis B. Magn Reson Med Sci 2015;14:211–21. 10.2463/mrms.2014-0150 - DOI - PubMed
    1. Ziol M, Handra-Luca A, Kettaneh A et al. . Noninvasive assessment of liver fibrosis by measurement of stiffness in patients with chronic hepatitis C. Hepatology 2005;41:48–54. 10.1002/hep.20506 - DOI - PubMed

Publication types

LinkOut - more resources