Skip to main page content (V体育平台登录)
U.S. flag

An official website of the United States government

Dot gov

The . gov means it’s official. Federal government websites often end in . gov or . mil. Before sharing sensitive information, make sure you’re on a federal government site VSports app下载. .

Https

The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely V体育官网. .

. 2015 Sep;19(9):1593-602.
doi: 10.1007/s11605-015-2835-y. Epub 2015 Apr 30.

Impact Total Psoas Volume on Short- and Long-Term Outcomes in Patients Undergoing Curative Resection for Pancreatic Adenocarcinoma: a New Tool to Assess Sarcopenia (V体育2025版)

Neda Amini  1 , Gaya Spolverato, Rohan Gupta, Georgios A Margonis, Yuhree Kim, Doris Wagner, Neda Rezaee, Matthew J Weiss, Christopher L Wolfgang, Martin M Makary, Ihab R Kamel, Timothy M Pawlik
Affiliations

Impact Total Psoas Volume on Short- and Long-Term Outcomes in Patients Undergoing Curative Resection for Pancreatic Adenocarcinoma: a New Tool to Assess Sarcopenia

VSports在线直播 - Neda Amini et al. J Gastrointest Surg. 2015 Sep.

Erratum in (V体育官网入口)

Abstract

Background: While sarcopenia is typically defined using total psoas area (TPA), characterizing sarcopenia using only a single axial cross-sectional image may be inadequate VSports手机版. We sought to evaluate total psoas volume (TPV) as a new tool to define sarcopenia and compare patient outcomes relative to TPA and TPV. .

Method: Sarcopenia was assessed in 763 patients who underwent pancreatectomy for pancreatic adenocarcinoma between 1996 and 2014 V体育安卓版. It was defined as the TPA and TPV in the lowest sex-specific quartile. The impact of sarcopenia defined by TPA and TPV on overall morbidity and mortality was assessed using multivariable analysis. .

Result: Median TPA and TPV were both lower in women versus men (both P < 0 V体育ios版. 001). TPA identified 192 (25. 1%) patients as sarcopenic, while TPV identified 152 patients (19. 9%). Three hundred sixty-nine (48. 4%) patients experienced a postoperative complication. While TPA-sarcopenia was not associated with higher risk of postoperative complications (OR 1. 06; P = 0. 72), sarcopenia defined by TPV was associated with morbidity (OR 1. 79; P = 0. 002). On multivariable analysis, TPV-sarcopenia remained independently associated with an increased risk of postoperative complications (OR 1. 69; P = 0. 006), as well as long-term survival (HR 1. 46; P = 0. 006). .

Conclusion: The use of TPV to define sarcopenia was associated with both short- and long-term outcomes following resection of pancreatic cancer. Assessment of the entire volume of the psoas muscle (TPV) may be a better means to define sarcopenia rather than a single axial image VSports最新版本. .

PubMed Disclaimer

Figures

Fig. 1
Fig. 1
Sarcopenia measurement at the level of L3 using (a) total psoas area (TPA) and (b) total psoas volume (TPV)
Fig. 2
Fig. 2
Comparison of sarcopenia distribution across gender and age: (a) distribution of TPV (cm3/m2) according to gender, (b) distribution of TPV (cm3/m2) according to age, (c) distribution of TPA (mm2/m2) according to gender and (d) distribution of TPA (mm2/m2) according to age
Fig. 3
Fig. 3
Percent of complication: (a) among sarcopenia patients vs. patients without sarcopenia and (b) among sarcopenic-obese patients vs. obese patients without sarcopenia
Fig. 4
Fig. 4
Overall survival according to total psoas volume (TPV) stratified by (a) sarcopenia patients vs. no sarcopenia patients (b) quartiles
See this image and copyright information in PMC

References

    1. Jemal A, Bray F, Center MM, Ferlay J, Ward E, Forman D. Global cancer statistics. CA: A Cancer Journal for Clinicians. 2011;61:69–90. - V体育ios版 - PubMed
    1. Winter J, Brennan M, Tang L, D’Angelica M, DeMatteo R, Fong Y, Klimstra D, Jarnagin W, Allen P. Survival after Resection of Pancreatic Adenocarcinoma: Results from a Single Institution over Three Decades. Annals of Surgical Oncology. 2012;19:169–75. - PubMed
    1. Serrano P, Cleary S, Dhani N, Kim PW, Greig P, Leung K, Moulton C-A, Gallinger S, Wei A. Improved Long-Term Outcomes After Resection of Pancreatic Adenocarcinoma: A Comparison Between Two Time Periods. Annals of Surgical Oncology. 2014:1–8. - PubMed
    1. DeOliveira ML, Winter JM, Schafer M, Cunningham SC, Cameron JL, Yeo CJ, Clavien P-A. Assessment of complications after pancreatic surgery: a novel grading system applied to 633 patients undergoing pancreaticoduodenectomy. Ann Surg. 2006;244:931. - PMC - PubMed
    1. Greenblatt DY, Kelly KJ, Rajamanickam V, Wan Y, Hanson T, Rettammel R, Winslow ER, Cho CS, Weber SM. Preoperative factors predict perioperative morbidity and mortality after pancreaticoduodenectomy. Annals of surgical oncology. 2011;18:2126–35. - PubMed

V体育官网 - MeSH terms