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. 2014 Dec;47(18):287-90.
doi: 10.1016/j.clinbiochem.2014.08.022. Epub 2014 Sep 7.

V体育平台登录 - Red blood cell distribution width and neutrophil/lymphocyte ratio are positively correlated with disease activity in primary Sjögren's syndrome

Zhi-De Hu  1 , Yi Sun  2 , Jie Guo  2 , Yuan-Lan Huang  3 , Bao-Dong Qin  4 , Qian Gao  2 , Qin Qin  2 , An-Mei Deng  5 , Ren-Qian Zhong  6
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Red blood cell distribution width and neutrophil/lymphocyte ratio are positively correlated with disease activity in primary Sjögren's syndrome

Zhi-De Hu et al. Clin Biochem. 2014 Dec.

Abstract

Objective: The red blood cell distribution width (RDW) and neutrophil/lymphocyte ratio (NLR) are increased in various inflammation related diseases, but their clinical significance in primary Sjögren's syndrome (pSS) has not been reported. The aim of the present study was to investigate the clinical significance of RDW and NLR in pSS patients VSports手机版. .

Methods: The medical records of pSS patients who were admitted to Changhai Hospital of the Second Military Medical University between April 2012 and December 2013 were retrospectively reviewed V体育安卓版. Correlations between RDW, NLR and the patient clinical characteristics were analyzed using the Spearman approach and the multiple linear regression model. .

Results: Fifty-two pSS patients and 58 healthy controls were enrolled. RDW and NLR were increased in pSS patients and positively correlated with the Sjögren's syndrome disease activity index (SSDAI). V体育ios版.

Conclusion: RDW and NLR may prove to be useful indices to estimate pSS disease activity VSports最新版本. .

Keywords: Disease activity; Neutrophil/lymphocyte ratio; Primary Sjögren's syndrome; Red blood cell distribution width V体育平台登录. .

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