Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The . gov means it’s official. Federal government websites often end in . gov or VSports app下载. mil. Before sharing sensitive information, make sure you’re on a federal government site. .

Https

The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely. V体育官网.

. 2012:2012:373219.
doi: 10.1155/2012/373219. Epub 2012 Aug 28.

Antitumor activities of kushen: literature review

Affiliations

Antitumor activities of kushen: literature review

V体育官网入口 - Mingyu Sun et al. Evid Based Complement Alternat Med. 2012.

VSports手机版 - Abstract

To discover and develop novel natural compounds with therapeutic selectivity or that can preferentially kill cancer cells without significant toxicity to normal cells is an important area in cancer chemotherapy. Kushen, the dried roots of Sophora flavescens Aiton, has a long history of use in traditional Chinese medicine to treat inflammatory diseases and cancer. Kushen alkaloids (KS-As) and kushen flavonoids (KS-Fs) are well-characterized components in kushen VSports手机版. KS-As containing oxymatrine, matrine, and total alkaloids have been developed in China as anticancer drugs. More potent antitumor activities were identified in KS-Fs than in KS-As in vitro and in vivo. KS-Fs may be developed as novel antitumor agents. .

PubMed Disclaimer

Figures

Figure 1
Figure 1
The molecular structure of antitumer compounds derived from Sophora flavescens.

"V体育2025版" References

    1. Sun FG, Sun XY, editors. Shen Nong Ben Cao Jing. 1st edition. Scientific and Technical Documents Publishing House; 1999. Sophora flavescens; p. p. 59.
    1. Zhonghua Bencao. 1st edition. Vol. 4. Shanghai Science and Technology Press; 1999. Sophora flavescens; pp. 634–643.
    1. Wang Y. Research progress on chemical constituents, preparative separation and quality of Sophora flavescens . Chinese Traditional Patent Medicine. 1997;19:39–41.
    1. Sun M, Han J, Duan J, et al. Novel antitumor activities of Kushen flavonoids in vitro and in vivo . Phytotherapy Research. 2007;21(3):269–277. - PubMed
    1. Cheng H, Xia B, Zhang L, et al. Matrine improves 2,4,6-trinitrobenzene sulfonic acid-induced colitis in mice. Pharmacological Research. 2006;53(3):202–208. - PubMed