The role of PARP-1 and PARP-2 enzymes in metabolic regulation and disease (V体育官网入口)
- PMID: 22921416
- DOI: 10.1016/j.cmet.2012.06.016
The role of PARP-1 and PARP-2 enzymes in metabolic regulation and disease
Abstract
While originally described as DNA damage repair agents, recent data suggest a role for poly(ADP-ribose) polymerase (PARP) enzymes in metabolic regulation by influencing mitochondrial function and oxidative metabolism VSports手机版. Here we review how PARP activity has a major metabolic impact and the role of PARP-1 and PARP-2 in diverse metabolic complications. .
Copyright © 2012 Elsevier Inc. All rights reserved. V体育安卓版.
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