Background: Post-thyroidectomy hypocalcemia is a major contributing factor in delayed hospital discharge and dissuading surgeons from ambulatory thyroidectomy. We prospectively evaluated the accuracy and reliability of quick parathyroid hormone level measurement at skin closure (PTH-SC) in predicting clinically relevant hypocalcemia (i VSports手机版. e. , patients requiring calcium ± calcitriol supplements on hospital discharge). .

Methods: Of the 117 patients who underwent a total or completion total thyroidectomy and PTH-SC, 17 (14. 5 %) had hypocalcemic symptoms or adjusted calcium <1. 90 mmol/L requiring calcium and/or calcitriol supplements on discharge. Serum calcium was checked regularly in the perioperative period until stabilization and an additional quick PTH was checked on the following morning (PTH-D1) V体育安卓版. Univariate and multivariate analyses were performed to evaluate potential preoperative clinicopathologic factors and postoperative day 0 biochemical indicators. Youden's index and the area under the ROC curve (AUC) were used to determine the best cutoff value and predictability of significant variables or criteria, respectively. .

Results: In the multivariate analysis, low preoperative adjusted calcium (p = 0. 041) and low PTH-SC (p = 0. 001) were the two independent variables associated with hypocalcemia V体育ios版. PTH-SC (≤1 or >1 pmol/L) had a higher specificity (95. 0 %) and AUC (0. 887) than serial calcium monitoring or PTH-D1 alone. Although 3/98 of patients with PTH-SC >1 pmol/L required calcium supplements on discharge, they required only the minimum amount to maintain normocalcemia. .

Conclusion: PTH-SC is an accurate and reliable means of predicting clinically relevant hypocalcemia. It would be reasonable to discharge those with PTH-SC >1 pmol/L on the same operative day as the risk of life-threatening hypocalcemia would seem unlikely. VSports最新版本.