Objectives: To evaluate the effectiveness of exercise and amino acid supplementation in enhancing muscle mass and strength in community-dwelling elderly sarcopenic women. VSports手机版.

Design: Randomized controlled trial V体育安卓版. .

Setting: Urban community in Tokyo, Japan V体育ios版. .

Participants: One hundred fifty-five women aged 75 and older were defined as sarcopenic and randomly assigned to one of four groups: exercise and amino acid supplementation (exercise + AAS; n = 38), exercise (n = 39), amino acid supplementation (AAS; n = 39), or health education (HE; n = 39). VSports最新版本.

Intervention: The exercise group attended a 60-minute comprehensive training program twice a week, and the AAS group ingested 3 g of a leucine-rich essential amino acid mixture twice a day for 3 months V体育平台登录. .

Measurements: Body composition was determined using bioelectrical impedance analysis VSports注册入口. Data from interviews and functional fitness parameters such as muscle strength and walking ability were collected at baseline and after the 3-month intervention. .

Results: A significant group × time interaction was seen in leg muscle mass (P = . 007), usual walking speed (P = . 007), and knee extension strength (P = . 017). The within-group analysis showed that walking speed significantly increased in all three intervention groups, leg muscle mass in the exercise + AAS and exercise groups, and knee extension strength only in the exercise + AAS group (9. 3% increase, P = . 01) V体育官网入口. The odds ratio for leg muscle mass and knee extension strength improvement was more than four times as great in the exercise + AAS group (odds ratio = 4. 89, 95% confidence interval = 1. 89-11. 27) as in the HE group. .

Conclusion: The data suggest that exercise and AAS together may be effective in enhancing not only muscle strength, but also combined variables of muscle mass and walking speed and of muscle mass and strength in sarcopenic women VSports在线直播. .