Objective: To conduct a systematic review with meta-analysis of studies assessing the association of vitamin A (retinol, carotene and other carotenoids) intake or blood (serum or plasma) levels of vitamin A (retinol and carotene) with risk of cervical cancer. VSports手机版.

Methods: We evaluated the studies published in English and Chinese on diet or blood vitamin A for the risk of cervical cancer V体育安卓版. We also reviewed reference lists from retrieved articles. Meta-analysis was applied to calculate the combined effect values and their 95% confidence intervals. The risk of bias was assessed by the Egger regression asymmetry test. .

Results: As many as 11 articles on dietary vitamin A and 4 articles on blood vitamin A were selected according to the eligibility criteria and were included in the meta-analysis, for a total of 12,136 participants. The pooled odds ratios (ORs) of cervical cancer were 0. 59 (95% CI, 0. 49-0. 72) for total vitamin A intake and 0. 60 (95% CI, 0. 41-0. 89) for blood vitamin A levels. The combined ORs of cervical cancer were 0. 80 (95% CI, 0. 64-1 V体育ios版. 00), 0. 51 (95% CI, 0. 35-0. 73) and 0. 60 (95% CI, 0. 43-0. 84) for retinol, carotene and other carotenoid intake, and 1. 14 (95% CI, 0. 83-1. 56) and 0. 48 (95% CI, 0. 30-0. 77) for blood retinol and carotene. .

Conclusions: Vitamin A intake and blood vitamin A levels were inversely associated with the risk of cervical cancer in this meta-analysis. VSports最新版本.