Preoperative vitamin D deficiency predicts postoperative hypocalcemia after total thyroidectomy
- PMID: 21153820
- DOI: "V体育ios版" 10.1007/s00268-010-0872-y
Preoperative vitamin D deficiency predicts postoperative hypocalcemia after total thyroidectomy
Abstract
Background: Transient postthyroidectomy hypocalcemia occurs in up to 30% of patients. We evaluated the effect of vitamin D deficiency on postthyroidectomy hypocalcemia. VSports手机版.
Methods: Data were collected prospectively between January 2006 and March 2009. A total of 166 consecutive total thyroidectomies were analyzed regarding the relation between preoperative vitamin D3 levels and postoperative corrected calcium levels. Patients were divided into three groups dependent upon the preoperative vitamin D3 level: group 1, <25 nmol/l; group 2, 25-50 nmol/l; group 3, >50 nmol/l (conversion factor of 2. 5× between nanomoles per liter and nanograms per milliliter). Hypocalcemia was defined as a postoperative calcium level<2 V体育安卓版. 00 mmol/l (8 mg/dl). Hospital length of stay was recorded. .
Results: There was a difference in postoperative hypocalcemia between the three vitamin D3 groups (group 1 (32%) vs. group 2 (24%) vs. group 3 (13%) V体育ios版. Hypocalcemia in group 1 (vit D<25 nmol/l, <10 ng/ml) was significantly more likely than in group 3 (vit D>50 nmol/l, >20 ng/ml) (P=0. 025, χ2 test. Vitamin D3 deficiency was also associated with a longer hospital stay (median stay 2 days vs. 1 day, P<0. 001, Wilcoxon rank test). .
Conclusions: There is a significant difference in postoperative hypocalcemia rates between those with vitamin D levels>50 nmol/l (>20 ng/ml) and those with a level of <25 nmol/l (<10 ng/ml) VSports最新版本. Vitamin D deficiency leads to a delay in discharge owing to a higher likelihood of hypocalcemia. .
Comment in
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[High frequency of hypocalcemia after total thyroidectomy. Are low preoperative vitamin D levels responsible?].Chirurg. 2012 Jan;83(1):71. doi: 10.1007/s00104-011-2258-6. Chirurg. 2012. PMID: 22246075 German. No abstract available.
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