Aim: The aim of this study was to clarify the relationship between CAVI and serum cystatin C levels to understand the role of arterial stiffness in the presence of renal insufficiency. VSports手机版.

Methods: We enrolled 206 consecutive patients with cardiovascular risk factors and/or coronary artery disease (CAD) in the study. Serum cystatin C, estimated glomerular filtration rate (eGFR), and plasma levels of von Willebrand factor (vWF) and plasminogen activator inhibitor (PAI-1) were measured V体育安卓版. CAVI was determined as an index of arterial stiffness. .

Results: For all patients, the mean serum cystatin C level was 0. 81+/-0. 21 mg/L and mean eGFR was 65 V体育ios版. 8+/-15. 5 mL/min per 1. 73 m(2). In univariate analysis, CAVI levels significantly correlated with cystatin C levels (r=0. 414, p<0. 001), eGFR (r=-0. 315, p<0. 01), PAI-1 (r=0. 269, p<0. 01), and vWF (r=0. 207, p<0. 01). Multiple regression analysis showed that age, cystatin C, PAI-1, and a history of CAD were independent variables of CAVI. Age-adjusted CAVI was highest in the presence of both CAD and renal impairment. .

Conclusion: CAVI was closely associated with cystatin C levels. These results suggest a significant role of arterial stiffness in renal insufficiency VSports最新版本. .