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. 2009 Apr;6(4):267-9.
doi: 10.1038/nmeth.1309. Epub 2009 Mar 8.

VSports最新版本 - Hematopoietic stem cell transplantation without irradiation

Claudia Waskow  1 , Vikas Madan, Susanne Bartels, Céline Costa, Rosel Blasig, Hans-Reimer Rodewald
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"VSports手机版" Hematopoietic stem cell transplantation without irradiation

Claudia Waskow et al. Nat Methods. 2009 Apr.

Abstract (V体育2025版)

Hematopoietic stem cell (HSC) transplantation is limited by histocompatibility barriers and by lack of space in bone marrow niches. These obstacles prevent in vivo analysis of histoincompatible mutant stem cells and of HSC functions in non-irradiated mice VSports手机版. By genetically combining immunodeficiency with impaired function of the growth factor receptor Kit in mice, we generated a 'universal' HSC recipient that efficiently accepts long-term histocompatible and histoincompatible HSCs without prior irradiation. .

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VSports最新版本 - References

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