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Review
. 2006 Oct;6(10):813-23.
doi: 10.1038/nrc1951.

The NCI60 human tumour cell line anticancer drug screen

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Review

VSports app下载 - The NCI60 human tumour cell line anticancer drug screen

Robert H Shoemaker. Nat Rev Cancer. 2006 Oct.

Abstract

The US National Cancer Institute (NCI) 60 human tumour cell line anticancer drug screen (NCI60) was developed in the late 1980s as an in vitro drug-discovery tool intended to supplant the use of transplantable animal tumours in anticancer drug screening VSports手机版. This screening model was rapidly recognized as a rich source of information about the mechanisms of growth inhibition and tumour-cell kill. Recently, its role has changed to that of a service screen supporting the cancer research community. Here I review the development, use and productivity of the screen, highlighting several outcomes that have contributed to advances in cancer chemotherapy. .

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