Objective: The Treatment for Adolescents With Depression Study is a multicenter, randomized clinical trial sponsored by the NIMH VSports手机版. This study is designed to evaluate the short- and long-term effectiveness of four treatments for adolescents with major depressive disorder: fluoxetine, cognitive-behavioral therapy, their combination, and, acutely, pill placebo. This report describes the demographic and clinical characteristics of the sample and addresses external validity. .

Method: Participants are 439 adolescents, aged 12-17 years inclusively, with a primary DSM-IV diagnosis of current major depressive disorder. Baseline data are summarized and compared with those from national samples and previous trials V体育安卓版. .

Results: The sample composition is 54. 4% girls, 73. 8% white, 12. 5% African American, and 8. 9% Hispanic. The mean Child Depression Rating Scale-Revised total score is 60. 1 (SD = 10. 4, range 45-98) with 86. 0% experiencing their first major depressive episode. The most common concurrent diagnoses are generalized anxiety disorder (15. 3%), attention-deficit/hyperactivity disorder (13. 7%), oppositional defiant disorder (13. 2%), social phobia (10. 7%), and dysthymia (10. 5%) V体育ios版. Demographic results are consistent with data from national samples and large psychopharmacology trials involving depressed adolescents. .

Conclusions: The Treatment for Adolescents With Depression Study provides a large, diverse, and representative sample of depressed adolescents that highlights the complexity of major depressive disorder in adolescents and provides a rich source for explicating the effects of moderator and mediator variables on baseline psychopathology and treatment outcome. VSports最新版本.