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Best CBD for Pain Management for 2025

This article discusses how CBD products may help relieve pain and provides a list of potentially effective CBD products that have undergone extensive third-party testing for safety.

Below, we compare the CBD products in this article for price, strength, and more.

ProductStrengthKey ingredientsPrice
Joy Organics
Joy Organics Broad Spectrum CBD Tincture
15 to 75 mg
broad-spectrum
• organic CBD
• olive oil
from $49.95
PlusCBD
PlusCBD Daily Topical 100 mg CBD Balm
100 mg
full-spectrum
• CBD
• almond oil
• beeswax
$35.99
Cornbread
Cornbread Hemp Distilled Oil
25 mg
full-spectrum
• CBD
• THC
• tapioca
• cane sugar
• pear juice
from $34.99
Medterra
Medterra Max Relief Gummies
25 mg
full-spectrum
• CBD
• THC
• tapioca
• cane sugar
• pear juice
from $34.99
Lazarus Naturals
Lazarus Naturals CBD Softgels
100 mg
full-spectrum
• CBD
• flaxseed oil
• coconut MCT oil
• sweet orange oil
$80
R&R
R&R CBD gummies
15 to 75 mg
full-spectrum
• CBD
• tapioca syrup & starch
• cane sugar
• fruit and vegetable extract
• sunflower oil
• natural flavors
from $55

Medical News Today chooses CBD products for pain relief based on criteria we think are good indicators of safety, quality, and transparency.

As a part of our vetting process, we consider:

  • the product’s composition, ingredients, and overall quality
  • any third-party certifications
  • the company’s reputation and business practices
  • any lab test results
  • marketing claims

Medical News Today follows a strict product selection and vetting process. Learn more here.

A person can consider the following when buying a CBD product for pain management:

  • Strength: CBD products come in a range of strengths. People who have not used CBD products before should start with a low-strength product and build up until they get the needed effects to manage their pain.
  • THC content: Hemp products with less than 0.3% THC are legal on a federal level. A person should check the THC content before making a purchase.
  • Hemp source: People can consider CBD products from companies that responsibly source their hemp. Many companies use hemp that grows in the United States.
  • Form: CBD products can come in oils, ointments, creams, patches, or gels. People can consider how convenient their chosen product will be to apply, whether it suits different skin types, and how long the product will last.
  • Cost: Some CBD products can be expensive. People should consider how often they will need to use their CBD product to manage their pain and choose a product that will fit their budget and be effective.
  • COA: A person should consider products from companies that provide a COA, a document containing information about the product’s CBD potency, THC and other cannabinoids, and safety test results. A person can find COAs on a brand’s website or by contacting the brand directly.
  • Reputable supplier: People should look for high quality products from reputable manufacturers and retailers when shopping for CBD. These companies test every batch of their products via an independent third-party lab for purity, showing that the product does not contain harmful metals or toxins. Products that undergo third-party testing will have a COA.

CBD comes in several different forms, all of which have different methods of application:

CBD gummies, capsules, and oils are for oral ingestion and may be better for aches and pains all over the body. On the other hand, people can apply topical products to specific body areas, such as sore muscles or aching joints.

CBD oils and tinctures are more versatile than other forms and usually come in tinted glass bottles with a dropper. People can either add a few drops of CBD oil to food or beverages or place it under their tongue.

It is important to discuss using CBD with a healthcare professional, especially if a person is already taking medication for pain. It is important not to go over the dose a product recommends, and to stop taking it immediately if a person experiences side effects.

There is some evidence that CBD can benefit pain. Read on to learn how effective CBD can be for inflammation, chronic pain, and arthritis.

CBD for inflammation

A 2020 review states that CBD can have a positive effect on inflammatory pain. However, many of the studies in the review were animal studies, and their results may not translate to humans. A 2021 review found that CBD, as well as other cannabinoids, could have an anti-inflammatory effect, which could pave the way toward human clinical trials. CBD may also increase levels of AEA, an endogenous cannabinoid that reduces pain.

CBD for chronic pain

A 2022 systematic review stated that some studies found CBD may be effective and safe for use in treating chronic pain. However, these initial results are not concrete enough to make specific recommendations for usage. Study authors stated that CBD could be an effective alternative to opioids because it does not have psychoactive effects and is not as likely to lead to dependence.

VSports在线直播 - CBD for arthritis pain

A 2022 study found that CBD improved pain in 83% of participants with arthritis. In addition, 66% also believed CBD improved their sleep quality and ability to move. The authors noted that participants with osteoarthritis found the most benefit in their movement and pain reduction when compared to those with rheumatoid arthritis and autoimmune arthritis.

Authors of a 2020 study also wrote that CBD exhibited anti-arthritis activity. They found that it targeted inflamed cells in the synovial fluid in the joints and improved rheumatoid arthritis.

While more research, such as large-scale, high quality clinical trials, is still necessary, these preliminary studies suggest CBD may help manage pain. A 2021 study also notes that participants in the research have positive attitudes toward CBD treatment options and report positive outcomes when using the substance for pain-related conditions.

How does CBD work for pain?

There are compounds in the cannabis plant called endogenous and exogenous cannabinoids. Endogenous cannabinoids are naturally occurring lipids that the body produces. However, the body does not produce exogenous cannabinoids. Exogenous cannabinoids include CBD, THC, cannabichromene (CBC), and cannabigerol (CBG).

Cannabinoids, both endogenous and exogenous, bind to endocannabinoid receptors attached to cells. These include cannabinoid 1 and cannabinoid 2 receptors. This binding action stimulates different cell responses that influence pain signaling pathways.

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Cons

V体育官网入口 - CBD resources

Visit our dedicated hub for more research-backed information and in-depth resources on CBD.

Side effects of CBD include:

More severe side effects include:

  • liver damage
  • fertility problems in males
  • potentially severe interactions with alcohol and certain medications

It’a wise to start at the lowest possible dose of CBD, then increase the dosage gradually until they reach their desired effect. However, they should not exceed their product’s recommended dosage.

Research is still yet to determine what CBD dose is most effective for pain management.

When buying CBD oil for pain, people can consider the type of CBD it contains and its potency. Full-spectrum oil may be stronger but can expose a person to THC. A stronger oil may have more noticeable effects but may not be suitable for beginners. People should also research brands to see if they recommend their CBD oils for pain.

The strength of CBD a person needs to manage pain depends on their individual condition and the severity of their pain. Ideally, a person needs to speak with a healthcare professional before taking any CBD for pain.

They need to start with the lowest dose possible and work up to a dose that has the desired effect in reducing their pain. However, a person should not exceed the maximum dose stated on the product label.

If a person is looking for targeted pain relief with a CBD product, a cream or ointment will be best. A CBD oil or gummy may be better for people who want more widespread pain relief.

A CBD cream, balm, or ointment may be best for back pain as a person can apply it directly to the painful area. However, people with back pain should speak with a doctor to understand the cause of their pain and the most effective treatments.

CBD for pain management shows promise in preliminary clinical studies, and animal studies suggest CBD may help relieve pain. However, more research is necessary to evaluate these findings.

CBD is generally safe but can lead to side effects, such as tiredness and appetite changes. People should speak with a doctor before using CBD for pain management, as there may be more appropriate treatments for their particular condition.

Is CBD legal?The 2018 Farm Bill removed hemp from the legal definition of marijuana in the Controlled Substances Act. This made some hemp-derived CBD products with less than 0.3% THC federally legal. However, CBD products containing more than 0.3% THC still fall under the legal definition of marijuana, making them federally illegal but legal under some state laws. Be sure to check state laws, especially when traveling. Also, keep in mind that the FDA has not approved nonprescription CBD products, and some products may be inaccurately labeled.

How we reviewed this article:

Medical News Today has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical journals and associations. We only use quality, credible sources to ensure content accuracy and integrity. You can learn more about how we ensure our content is accurate and current by reading our editorial policy.

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