凤凰彩票大厅app官网 - IgA Nephropathy: Risk Factors and Causes

  • Health Conditions (VSports手机版)

    All
    • Breast Cancer
    • Cancer Care
    • Caregiving for Alzheimer's Disease (V体育ios版)
    • Chronic Kidney Disease (VSports在线直播)
    • Chronic Obstructive Pulmonary Disease (COPD)
    • Digestive Health
    • VSports注册入口 - Eye Health
    • Heart Health (VSports注册入口)
    • Menopause
    • V体育官网 - Mental Health
    • Migraine
    • Multiple Sclerosis (MS)
    • Parkinson’s Disease
    • Psoriasis
    • Rheumatoid Arthritis (RA)
    • Sleep Health
    • Type 2 Diabetes
    • Weight Management

    Condition Spotlight

    All
    • Controlling Ulcerative Colitis
    • Navigating Life with Bipolar Disorder
    • Mastering Geographic Atrophy
    • Managing Type 2 Diabetes

  • Wellness Topics

    All
    • CBD
    • Fitness
    • VSports手机版 - Healthy Aging
    • Hearing
    • Mental Well-Being
    • Nutrition
    • Parenthood (VSports在线直播)
    • V体育安卓版 - Recipes
    • Sexual Health
    • Skin Care
    • Sleep Health
    • Vitamins and Supplements
    • Women's Wellness

    "V体育官网" Product Reviews

    All
    • "VSports最新版本" At-Home Testing
    • Men's Health
    • Mental Health
    • Nutrition
    • Sleep
    • Vitamins and Supplements
    • Women's Health

    Featured Programs

    All
    • "VSports手机版" Your Guide to Glucose Health
    • Inflammation and Aging
    • VSports -
      Cold & Flu Season Survival Guide
    • She’s Good for Real

  • "V体育安卓版" Featured

    • Video Series
    • "V体育官网入口" Pill Identifier
    • V体育2025版 - FindCare
    • Drugs A-Z
    • V体育官网入口 - Medicare Plans by State

    "V体育安卓版" Lessons

    All
    • Crohn’s and Ulcerative Colitis Essentials
    • V体育平台登录 - Diabetes Nutrition
    • V体育ios版 - High Cholesterol
    • Taming Inflammation in Psoriasis
    • Taming Inflammation in Psoriatic Arthritis

    Newsletters

    All
    • "VSports app下载" Anxiety and Depression
    • Digestive Health
    • Heart Health
    • Migraine
    • Nutrition Edition
    • Type 2 Diabetes
    • Wellness Wire

    Lifestyle Quizzes

    • Find a Diet
    • "V体育官网入口" Find Healthy Snacks
    • Weight Management
    • How Well Do You Sleep?
    • "VSports注册入口" Are You a Workaholic?

  • Health News

    All
    • Medicare 2026 Changes
    • Can 6-6-6 Walking Workout Help You Lose Weight?
    • This Couple Lost 118 Pounds Together Without Medication
    • "V体育官网入口" 5 Science-Backed Ways to Live a Longer Life
    • Morning Coffee May Help You Live Longer

    This Just In

    • 5 Tips for a Healthy Lifestyle
    • How to Disinfect Your House After the Flu
    • Best Vegan and Plant-Based Meal Delivery for 2025
    • Does Medicare Cover Pneumonia Shots?
    • Chromosomes, Genetics, and Your Health

    Top Reads

    • Best Multivitamins for Women
    • Best Multivitamins for Men (V体育2025版)
    • Best Online Therapy Services
    • Online Therapy That Takes Insurance (V体育官网入口)
    • Buy Ozempic Online
    • Mounjaro Overview

    V体育ios版 - Video Series

    • Youth in Focus
    • Healthy Harvest
    • Through an Artist's Eye
    • Future of Health

  • "V体育官网入口" Find Your Bezzy Community

    Bezzy communities provide meaningful connections with others living with chronic conditions. Join Bezzy on the web or mobile app.

    All
    • Breast Cancer
    • Multiple Sclerosis (VSports在线直播)
    • Depression
    • VSports注册入口 -
      Migraine
    • Type 2 Diabetes
    • "VSports app下载" Psoriasis

    Follow us on social media

    Can't get enough. Connect with us for all things health VSports app下载.

Explore more in
Nephropathy

Related Hubs

Chronic Kidney Disease

Chronic Kidney Disease

Your hub for managing your chronic kidney disease

Related Topics

  • Related Articles

    • Diagnosis

  • Related Hub

    Navigating Dialysis

    "VSports" Navigating Dialysis

    Tips and tools for managing your health and well-being during dialysis

    Related ArticlesWhat Is a Nephrologist. Treatment

    Causes & Risk FactorsRelated ArticlesVSports最新版本 - Contrast InducedOxalate Nephropathy"VSports最新版本" Reflux NephropathyPain Reliever UseCauses & Risk Factors

    PrognosisRelated ArticlesOutlook

    TypesRelated ArticlesC3G and IgANDiabetic NephropathyIgA (Berger's Disease)Membranous Glomerulonephritis

    ComplicationsRelated ArticlesKidney FailureNavigating IgA NephropathyContent created by Healthline and supported by advertising V体育安卓版. Learn more

    Risk Factors and Causes of IgA Nephropathy (V体育ios版)

    Medically reviewed by Megan Soliman, MD — Written by Stephanie Watson — Updated on July 2, 2025"V体育平台登录" Risk factorsCausesTakeaway

    Key takeaways

    IgA nephropathy is a disease that causes the protein immunoglobulin A (IgA) to build up in your kidneys. Factors like sex, race, and family history may increase your chance of developing the condition, but the exact cause isn’t clear. The condition happens when antibodies attach to IgA, thinking it’s an invading cell. Clumps of IgA and antibodies then get stuck in your kidneys and cause damage. IgA nephropathy may lead to end-stage kidney disease, which can be life threatening without treatment. IgA nephropathy is also called Berger’s disease. IgA normally helps your body fight infections, but when it gets stuck inside your kidneys, it leads to loss of function.

    IgA builds up and damages the tiny kidney filters, called glomeruli, that remove waste and extra fluids from the blood V体育ios版. This damage makes the kidneys leak blood and protein into the urine.

    The kidneys eventually get so scarred that they can’t filter the blood well enough to keep you healthy VSports最新版本. The final stage of kidney disease is called end-stage kidney disease, also called end-stage renal disease (ESRD). At that point, you will need dialysis or a kidney transplant to filter your blood instead of your damaged kidneys.

    Risk factors (V体育ios版)

    Share on PinterestDesign by Maya ChastainCertain factors make some people more likely than others to get IgA nephropathy V体育平台登录. But just because you have some or all of these risks doesn’t mean you will get this disease.

    IgA nephropathy is about two times more common in men than women in the United States VSports注册入口. Men in their teens to late 30s are most likely to get this condition.

    Asians, Native Americans, and white Americans are at higher risk for IgA nephropathy, although this condition can affect people of any race.

    Your risk increases if you have a family history of IgA nephropathy. Up to 40% of people with a parent, sibling, or child who has IgA nephropathy also have abnormal IgA VSports在线直播.

    Risk for end-stage renal disease

    . Share on Pinterest
    Medical Illustration by Maya Chastain

    According to some research, approximately 1 in 4 people with IgA nephropathy will develop ESRD within 10–20 years of their diagnosis.

    Your risk of developing ESRD from IgA nephropathy is higher if:

    • your kidney function continues to decline
    • your blood test results are abnormal
    • you have high blood pressure

    "V体育2025版" Causes of IgA nephropathy

    Researchers don’t know exactly what causes IgA nephropathy. They believe it results from a faulty immune system response that attacks and damages the kidneys VSports app下载. Here’s what happens:.

    Share on Pinterest
    Medical Illustration by Maya Chastain
    1. IgA, a protein that helps the immune system fight infections, contains less of the sugar galactose than normal.
    2. Antibodies in the blood see the IgA as foreign and attach to it, forming clumps.
    3. Those clumps are too big to fit through the kidney filters, so they get stuck inside.
    4. The trapped IgA inflames and damages the kidneys, causing them to leak blood and protein.
    5. Over time, the kidneys become too damaged to filter the blood.

    The takeaway

    IgA nephropathy is a type of kidney disease V体育官网. It’s most common in younger Asian, Native American, and white men. Having a family history of the disorder also increases your risk.

    The condition happens when antibodies attach to IgA, thinking it’s an invading cell. Clumps of IgA and antibodies then get stuck in your kidneys and cause damage VSports手机版.

    IgA nephropathy may lead to end-stage kidney disease, which can be life threatening without treatment.

     

    How we reviewed this article:

    Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical journals and associations. We only use quality, credible sources to ensure content accuracy and integrity. You can learn more about how we ensure our content is accurate and current by reading our editorial policy.
    • IgA nephropathy. (2022).
      https://www.niddk.nih.gov/health-information/kidney-disease/iga-nephropathy
    • IgA nephropathy. (2023).
      "VSports最新版本" https://www.kidneyfund.org/all-about-kidneys/other-kidney-diseases/iga-nephropathy
    • IgA nephropathy. (n.d.)
      "V体育官网" https://www.kidney.org/atoz/content/iganeph
    • Jarrick S, et al. (2019). Mortality in IgA nephropathy: A nationwide population-based cohort study.
      https://journals.lww.com/JASN/Fulltext/2019/05000/Mortality_in_IgA_Nephropathy__A_Nationwide.17.aspx
    • Rajasekaran A, et al. (2021). IgA nephropathy: An interesting autoimmune kidney disease.
      https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8577278/
    • Rawla P, et al. (2023). IgA nephropathy.
      https://www.ncbi.nlm.nih.gov/books/NBK538214/
    • Sato Y, et al. (2021.) Positive renal familial history in IgA nephropathy is associated with worse renal outcomes: a single-center longitudinal study.
      https://bmcnephrol.biomedcentral.com/articles/10.1186/s12882-021-02425-8
    • Shu D, et al. (2017). Risk factors of progressive IgA nephropathy which progress to end stage renal disease within ten years: a case-control study.
      https://bmcnephrol.biomedcentral.com/articles/10.1186/s12882-016-0429-x

    Share this article

    Medically reviewed by Megan Soliman, MD — Written by Stephanie Watson — Updated on July 2, 2025

    More in Navigating IgA Nephropathy

    • What to Know About Tonsillectomy for IgA Nephropathy
    • What Is Nephrology and What Does a Nephrologist Do?
    • Immunoglobulins and Immunoglobulin Blood Tests: Function and Purpose
    • Medical Conditions and Lifestyle Factors that Can Damage Your Kidneys
    • View all

"V体育官网入口" Read this next

  • What to Know About Tonsillectomy for IgA Nephropathy

    Research shows that tonsillectomy may help slow the development of IgA nephropathy. Here's what to know about this procedure to remove the tonsils.

    READ MORE
  • What Is Nephrology and What Does a Nephrologist Do?

    If you're wondering what a nephrologist is, we can tell you about this medical specialist and what they do to monitor and treat your kidneys.

    READ MORE
  • Immunoglobulins and Immunoglobulin Blood Tests: Function and Purpose

    Learn more about immunoglobulins including how they help your body fight infections and the tests doctors use to measure your immunoglobulin levels.

    READ MORE
  • Medical Conditions and Lifestyle Factors that Can Damage Your Kidneys

    Some medical conditions, medications, and lifestyle habits can cause damage to your kidneys. Many are modifiable, and you can take steps to manage…

    READ MORE
© 2025 Healthline Media LLC. All rights reserved. Healthline Media is an RVO Health Company. Our website services, content, and products are for informational purposes only. Healthline Media does not provide medical advice, diagnosis, or treatment. See additional information.
  • "VSports app下载" About Us
  • "V体育ios版" Contact Us
  • V体育平台登录 - Terms of Use
  • V体育官网入口 - Privacy Policy
  • Advertising Policy
  • Health Topics
  • Sitemap (V体育官网入口)
  • Medical Affairs (VSports手机版)
  • "V体育官网入口" Content Integrity
  • Newsletters
  • Your Privacy Choices
  • © 2025 Healthline Media LLC. All rights reserved. Healthline Media is an RVO Health Company. Our website services, content, and products are for informational purposes only. Healthline Media does not provide medical advice, diagnosis, or treatment. See additional information.
© 2025 Healthline Media LLC. All rights reserved. Healthline Media is an RVO Health Company. Our website services, content, and products are for informational purposes only. Healthline Media does not provide medical advice, diagnosis, or treatment. See additional information.
AboutCareersAdvertise with us

OUR BRANDS

HealthlineMedical News TodayGreatistPsych CentralBezzy
<sup dir="aH18E"></sup>