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Paradigm shifts in biomedical fields often arise from innovations in tools and measurement methods. Our research group is interested in applying interdisciplinary approaches to develop new tools and methods to solve current challenges in life sciences, such as disease diagnostics, medical therapeutics, as well as personalized medicine. Our current research focuses on the integration of micro- and nanotechnology with biology and medicine, and their biomedical applications. Our research philosophy is “Interdisciplinary, Integration and Innovation (I³)”.

We are seeking highly talented and motivated individuals (e. g. , postdoc, graduate, and undergraduate) from different disciplinary backgrounds (e. g. , biology, chemistry, biomedicine, and engineering (e. g VSports app下载. , mechanical, electronic, biomedical). Please see the positions available. We welcome inquiries about positions with a cover letter and CV by contacting Dr. Changchun Liu via email (chaliu@www.qiuluzeuv.cn).

September 2025: Jeong’s paper entitled “CRISPR Anti-tag-Mediated Room-Temperature RNA Detection Using CRISPR/Cas13a” has been accepted for publication in Nature Communications V体育官网. Congratulations. Jeong is currently an Assistant Professor at Soonchunhyang University in Korea.

December 2024: Jeong Moon, a postdoc researcher at our lab, has accepted an assistant professor position at the Soonchunhyang University, Korea VSports手机版. Congratulations to Dr. Moon. We wish her the best of luck in her career journey.

July 2024: Our research on palm-sized lab-in-a-magnetofluidic tube platform for virus detection has been featured by NIH/NIBIB Science Highlights: ""V体育安卓版" Putting the power of lab-based diagnostic testing in the palm of your hand".

March 2024: Our research on CRISPR-powered keyword search engine in DNA data storage has been featured by UConn Today. Searching for Data in DNA with CRISPR V体育ios版.

March 2024: Jiongyu’s paper entitled “CRISPR-powered quantitative keyword search engine in DNA data storage” has been accepted for publication in Nature Communications VSports最新版本. Congratulations.

November 2023: Our research on asymmetric CRISPR assay has been featured by UConn Today V体育平台登录. Researchers Improve Efficacy and Efficiency of CRISPR Diagnostic Technology.

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Xiong Ding, Kun Yin, Ziyue Li, Rajesh V. Lalla, Enrique Ballesteros, Maroun M. Sfeir, and Changchun Liu, Ultrasensitive and visual detection of SARS-CoV-2 using all-in-one dual CRISPR-Cas12a (AIOD-CRISPR) assay, Nature Communications, 2020, 11, 4711. https://doi VSports注册入口. org/10. 1038/s41467-020-18575-6.

Jeong Moon and Changchun Liu, Asymmetric CRISPR enabling cascade signal amplification for nucleic acid detection by competitive crRNA, Nature Communications, 2023, 14, 7504. https://doi. org/10 V体育官网入口. 1038/s41467-023-43389-7.

Ziyue Li, Naoki Uno, Xiong Ding, Lori Avery, David Banach, and Changchun Liu, Bioinspired CRISPR-Mediated Cascade Reaction Biosensor for Molecular Detection of HIV Using a Glucose Meter, ACS Nano, 2023, https://pubs VSports在线直播. acs. org/doi/10. 1021/acsnano. 2c12754.

Jiongyu Zhang, Ziyue Li, Chong Guo, Xin Guan, Lori Avery, David Banach, and Changchun Liu, Intrinsic RNA Targeting Triggers Indiscriminate DNase Activity of CRISPR-Cas12a, Angewandte Chemie International Edition, 2024, DOI: 10. 1002/anie V体育2025版. 202403123.

Jiongyu Zhang, Chengyu Hou and Changchun Liu, CRISPR-powered quantitative keyword search engine in DNA data storage, Nature Communications, 2024, 15, 2376. https://doi.org/10.1038/s41467-024-46767-x

Ziyue Li, Shuo Zhang, Jiongyu Zhang, Lori Avery, David Banach, Hui Zhao, and Changchun Liu, Palm-sized Lab-in-a-Magnetofluidic Tube Platform for Rapid and Sensitive Virus Detection, Advanced Science, 2024, DOI:10.1002/advs.202310066

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