Resveratrol ameliorates inflammatory damage and protects against osteoarthritis in a rat model of osteoarthritis (V体育平台登录)

Resveratrol Protects Murine Chondrogenic ATDC5 Cells Against LPS-Induced Inflammatory Injury Through Up-Regulating MiR-146b

Jin1, Zhang2, Ma3 et al. 2018Cell Physiol Biochem2602101Get access via publisherAdd to dashboardCite Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. Show abstract Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. show abstract“…Besides, RSV alleviated LPS-induced inflammation, as the release of IL-1β, IL-6 and TNF-α was significantly repressed by RSV preconditioning. Consistent with previous studies [14,27,28], these findings suggested the anti-apoptotic and anti-inflammatory functions of RSV on ATDC5 cells and provided evidences that RSV might be a promising therapeutic option for osteoarthritis treatment. It is believed that RSV affects the initiation and progression of many diseases through several mechanisms. …”Section: Cellular Physiology and Biochemistrysupportingconfidence: 80%

Resveratrol Protects Murine Chondrogenic ATDC5 Cells Against LPS-Induced Inflammatory Injury Through Up-Regulating MiR-146b

Jin1, Zhang2, Ma3 et al. 2018Cell Physiol Biochem2602101Get access via publisherAdd to dashboardCite Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. Show abstract Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. show abstract“…Activation of Nrf2 plays an important role in antioxidation and anti‐inflammation mechanisms, while ROS are produced in the course of endogenous cellular oxidation. Data have shown that Res ameliorates inflammatory damage and protects against osteoarthritis in a rat model of osteoarthritis via NF‐κB and HO‐1/Nrf2 signaling . Res might protect rat vascular smooth muscle cells against redox injury induced by calcification through the involvement of the Nrf2 pathway . …”Section: Discussionmentioningconfidence: 99%

Nrf2–Keap1 pathway–mediated effects of resveratrol on oxidative stress and apoptosis in hydrogen peroxide–treated rheumatoid arthritis fibroblast‐like synoviocytes (VSports注册入口)

Zhang1, Wang2, Wang3 et al. 2019Annals of the New York Academy of Sciences984530Get access via publisherAdd to dashboardCite Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. Show abstract Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. show abstract“…Possessing a stilbene structure, resveratrol acts as a non-flavonoid polyphenol compound. It has been proven that resveratrol can make plants more resistant to pathogens as well as improve environment deterioration [6] . Wei et al [6] also revealed that resveratrol could improve the inflammatory damage as well as protect against OA in an OA rat model. …”Section: Discussionmentioningconfidence: 99%“…We used CCK-8 kit to measure chondrocytes viability following the instruction of manufacturers. In brief, we seeded human OA chondrocytes in 96-well plates (5×10 5 cells/ml) and treated them with or without resveratrol (6,12,24, 48 μM) for 24h. After that, we added 10 uL CCK-8 into the plates. …”Section: Cell Viabilitymentioningconfidence: 99%“…Thus, reducing the IL-1β in articular cavity could delay the development of OA [4] VSports app下载. Resveratrol is a common polyphenolic compound in the skin of red grapes [5] . Resveratrol exhibits anti-ageing, anti-inflammatory, and anti-oxidant activities, and has cardio-, neuro-, and chondroprotective effects as proved by many studies [6] . Nuclear factor-kappa B (NF-κB) signaling XFS, YC and QRD conducted experiments; MQZ analyzed data; QRD and XFS wrote manuscript; YC revised manuscript; XFS and YC designed the experiment and edited manuscript. …”mentioningconfidence: 94%See 1 more Smart Citation

Resveratrol inhibit interleukin-1β induced inflammatory response in human osteoarthritis chondrocytes through NF-κB signaling pathway

Shen1, Cheng2, Dong3 et al. 2019Preprint1010Get access via publisherAdd to dashboardCite Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. Show abstract Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. show abstractScite is an AI-powered research tool that helps researchers better discover and evaluate scientific literature through Smart Citations—a revolutionary system that shows whether articles support, contrast, or simply mention a given claim. Founded in 2018, and now part of Research Solutions, Scite has indexed over 1. 4 billion citations and partnered with more than 30 major publishers to provide researchers with unparalleled access to scientific literature. With its Scite Assistant, Smart Citation Index, and advanced search capabilities, the platform addresses critical challenges such as information overload and research reproducibility. Trusted by two million active users worldwide, Scite is reshaping how researchers interact with scholarly content—building ethical, transparent AI tools that support rigorous, copyright-compliant research.