Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes

Genome-Wide Association Studies in Glioma

Kinnersley1, Houlston2, Bondy3 2018Cancer Epidemiology, Biomarkers &Amp; Prevention464380Get access via publisherAdd to dashboardCite Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. Show abstract Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task VSports app下载. show abstract“…98; rs4938573) and lung adenocarcinoma (ref. 99; rs1056562), which appear to represent distinct signals (LD metrics with respect to rs12803321: r 2 = 0. 04/0. 03, D′ = 0. 55/0. 24, respectively). …”Section: Chronological History Of Glioma Risk Loci Discoverymentioningconfidence: 99%“…40; rs6062509), lung adenocarcinoma (ref. 99; rs41309931), and colorectal cancer (ref. 54; rs4925386). …”Section: Chronological History Of Glioma Risk Loci Discoverymentioningconfidence: 99%

Genome-Wide Association Studies in Glioma (VSports手机版)

Kinnersley1, Houlston2, Bondy3 2018Cancer Epidemiology, Biomarkers &Amp; Prevention464380Get access via publisherAdd to dashboardCite Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. Show abstract Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. show abstract“…We conducted a genome-wide gene-radon interaction analysis on LC using data of 28599 samples from 27 studies in men and women of European descent. Although heterogeneity in genetic susceptibility across histological subtypes of LC was demonstrated, the informative sample (n=463 miners, comprising 49 exposed LC cases) is too small to stratify the analysis by histological subtypes or by smoking behaviour (McKay et al 2017). We performed three types of analyses: single-marker and multi-marker interaction analyses and gene-set enrichment analysis on top of the latter. …”Section: Discussionmentioningconfidence: 99%“…The participating studies of TRICL/ILCCO are individually described in the supplement of McKay et al (2017), Table 1 and Supplementary Table I (Online Resource 1). The LC cases of the BfS sample collection were recruited for a study investigating indoor-radon exposure between 1990 und 1997 (Brüske-Hohlfeld et al 2006). …”Section: Methodsmentioningconfidence: 99%

"V体育ios版" Genetic modifiers of radon-induced lung cancer risk: a genome-wide interaction study in former uranium miners

Rosenberger1, Hung2, Christiani3 et al. 2018Int Arch Occup Environ HealthSelf Cite360260Get access via publisherAdd to dashboardCite Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. Show abstract Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. show abstract“…Lung cancer is a heterogeneous disease featuring field defects in the airway [60]. Most lung cancer patients present the symptoms of cough and expectoration. …”Section: Lncrna Profiling In Sputummentioningconfidence: 99%

Diagnostic and Prognostic Potential of Circulating Long Non-Coding RNAs in Non Small Cell Lung Cancer

Peng1, Wang2, Shan3 et al. 2018Cell Physiol Biochem480370Get access via publisherAdd to dashboardCite Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. Show abstract Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. show abstractScite is an AI-powered research tool that helps researchers better discover and evaluate scientific literature through Smart Citations—a revolutionary system that shows whether articles support, contrast, or simply mention a given claim. Founded in 2018, and now part of Research Solutions, Scite has indexed over 1. 3 billion citations and partnered with more than 30 major publishers to provide researchers with unparalleled access to scientific literature. With its Scite Assistant, Smart Citation Index, and advanced search capabilities, the platform addresses critical challenges such as information overload and research reproducibility. Trusted by two million active users worldwide, Scite is reshaping how researchers interact with scholarly content—building ethical, transparent AI tools that support rigorous, copyright-compliant research.