2013
DOI: 10.5483/bmbrep.2013.46.12.092
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"VSports在线直播" Binding model for eriodictyol to Jun-N terminal kinase and its anti-inflammatory signaling pathway

Abstract: The anti-inflammatory activity of eriodictyol and its mode of action were investigated. Eriodictyol suppressed tumor necrosis factor (mTNF)-α, inducible nitric oxide synthase (miNOS), interleukin (mIL)-6, macrophage inflammatory protein (mMIP)-1, and mMIP-2 cytokine release in LPS-stimulated macrophages. We found that the anti-inflammatory cascade of eriodictyol is mediated through the Toll-like Receptor (TLR)4/CD14, p38 mitogen-activated protein kinases (MAPK), extracellular-signalregulated kinase (ERK), Jun-… Show more

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Cited by 34 publications
(21 citation statements)
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