V体育ios版 - Inflammation and neural signaling

A review of the neuro- and systemic inflammatory responses in post concussion symptoms: Introduction of the “post-inflammatory brain syndrome” PIBS

Rathbone1, Tharmaradinam2, Jiang3 et al. 2015Brain, Behavior, and Immunity903820Get access via publisherAdd to dashboardCite Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC) VSports app下载. Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. Show abstract Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. “…Speculation exists about a role for inflammation in the cancer treatment-related syndrome cluster due to the stimulation of Il-1b production in macrophages in response to some chemotherapeutic agents. While increased levels of peripheral Il-1b are not seen in humans after chemotherapy, increased levels of Il-6 and Il-1ra are seen in the treatment-related symptom cluster and are correlated with fatigue and sleep changes, and these markers are proposed as markers of central Il-1b activity (Wood and Weymann, 2013). In women with ovarian cancer, both before and after surgery, sleep disturbances are associated with higher levels of Il-6 (Clevenger et al, 2012). …”Section: Insomnia or Sleep Disturbances And Inflammationmentioningconfidence: 98%

A review of the neuro- and systemic inflammatory responses in post concussion symptoms: Introduction of the “post-inflammatory brain syndrome” PIBS

Rathbone1, Tharmaradinam2, Jiang3 et al. 2015Brain, Behavior, and Immunity903820Get access via publisherAdd to dashboardCite Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. Show abstract Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. “…Mounting evidence indicates that CRF and depressed mood are associated with elevated serum levels of pro-inflammatory mediators, including C-reactive protein (Pertl et al, 2013) and cytokines such as tumor necrosis factor-alpha (TNFα), interleukin (IL)-1β and IL-6 (Saligan and Kim, 2012; Wood and Weymann, 2013). These cytokines are likely produced by the tumor and host tissues in response to tumor growth or anti-tumor treatments (Wang et al, 2012). …”Section: Introductionmentioningconfidence: 99%“…The central nervous system (CNS) interprets inflammatory responses that originate in the periphery. Microglia, innate immune cells of the CNS, contribute to the propagation of inflammatory cytokines and secondary messengers throughout the CNS (Wood and Weymann, 2013). Increases in brain IL-1β are linked to both muscle atrophy (Braun et al, 2011) and depressed mood (Haroon et al, 2012). …”Section: Introductionmentioningconfidence: 99%

Tumor growth increases neuroinflammation, fatigue and depressive-like behavior prior to alterations in muscle function

Norden1, Bicer2, Clark3 et al. 2015Brain, Behavior, and Immunity114131172Get access via publisherAdd to dashboardCite Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. Show abstract Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. show abstract“…Mounting evidence from both clinical and preclinical studies indicates that elevations in pro-inflammatory cytokines may function as a common mechanism for the frequent association of fatigue and depression in patients with CRF. For instance, elevated serum levels of pro-inflammatory cytokines, such as tumor necrosis factor-alpha (TNFα), interleukin (IL)-1β and IL-6, are associated with fatigue in cancer patients [12, 13]. Increases in systemic inflammation are relayed to the brain where inflammation is propagated by innate immune cells [14]. …”Section: Introductionmentioningconfidence: 99%

Fluoxetine prevents the development of depressive-like behavior in a mouse model of cancer related fatigue

Norden1, Devine2, Bicer3 et al. 2015Physiology & Behavior463290Get access via publisherAdd to dashboardCite Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. Show abstract Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. show abstractScite is an AI-powered research tool that helps researchers better discover and evaluate scientific literature through Smart Citations—a revolutionary system that shows whether articles support, contrast, or simply mention a given claim. Founded in 2018, and now part of Research Solutions, Scite has indexed over 1. 4 billion citations and partnered with more than 30 major publishers to provide researchers with unparalleled access to scientific literature. With its Scite Assistant, Smart Citation Index, and advanced search capabilities, the platform addresses critical challenges such as information overload and research reproducibility. Trusted by two million active users worldwide, Scite is reshaping how researchers interact with scholarly content—building ethical, transparent AI tools that support rigorous, copyright-compliant research.