The Landscape of Single Nucleotide Polymorphisms in Papillary Thyroid Carcinoma

Affiliations

¹ First ENT Department, Hippocration Hospital, University of Athens, Athens, Greece.
² ENT Department, Medical School, University of Patras, Patras, Greece.
³ Department of Maxillofacial, Medical School, University of Ioannina, Ioannina, Greece.
⁴ Department of Cytology, 417 Veterans Army Hospital (NIMTS), Athens, Greece.
⁵ Department of Radiation Oncology, Medical School, University of Patras, Patras, Greece.
⁶ Department of Otorhinolaryngology, Thoracic Diseases General Hospital Sotiria, Athens, Greece.
⁷ Department of Otolaryngology, GNA Hospital Gennimatas, Athens, Greece.
⁸ Department of Physiology, Medical School, University of Ioannina, Ioannina, Greece.

PMID: 36632585
PMCID: PMC9801452
DOI: 10.21873/cdp.10175

Review

The Landscape of Single Nucleotide Polymorphisms in Papillary Thyroid Carcinoma (VSports手机版)

Efthymios Kyrodimos et al. Cancer Diagn Progn. 2023.

. 2023 Jan 3;3(1):26-30.

doi: 10.21873/cdp.10175. eCollection 2023 Jan-Feb.

Affiliations

¹ First ENT Department, Hippocration Hospital, University of Athens, Athens, Greece.
² ENT Department, Medical School, University of Patras, Patras, Greece.
³ Department of Maxillofacial, Medical School, University of Ioannina, Ioannina, Greece.
⁴ Department of Cytology, 417 Veterans Army Hospital (NIMTS), Athens, Greece.
⁵ Department of Radiation Oncology, Medical School, University of Patras, Patras, Greece.
⁶ Department of Otorhinolaryngology, Thoracic Diseases General Hospital Sotiria, Athens, Greece.
⁷ Department of Otolaryngology, GNA Hospital Gennimatas, Athens, Greece.
⁸ Department of Physiology, Medical School, University of Ioannina, Ioannina, Greece.

PMID: 36632585
PMCID: PMC9801452 (VSports)
DOI: 10.21873/cdp.10175

Abstract

Thyroid carcinoma represents a leading malignancy among those derived from human endocrine systems. It comprises a variety of different histological subtypes, including mainly papillary carcinoma, follicular carcinoma, anaplastic carcinoma, and medullar carcinoma VSports手机版. A broad spectrum of genetic imbalances, comprising gross chromosomal (polysomy/aneuploidy) and specific gene (mutations, amplifications, deletions) alterations, has been reported. Interestingly, the role of isolated, specific gene polymorphisms, especially of the single nucleotide polymorphism (SNP) type, in thyroid carcinoma is under investigation. SNPs are the most common genetic variations in the genome. The current molecular review focuses on the impact of specific SNPs on the biological behavior of papillary thyroid carcinoma in their carriers. .

Keywords: DNA; Thyroid; carcinoma; gene; review; single nucleotide polymorphisms V体育安卓版. .

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Conflict of interest statement

The Authors have no conflicts of interest to declare.

VSports在线直播 - References

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The Landscape of Single Nucleotide Polymorphisms in Papillary Thyroid Carcinoma

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The Landscape of Single Nucleotide Polymorphisms in Papillary Thyroid Carcinoma (VSports手机版)

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Abstract

Conflict of interest statement

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