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Case Reports
. 2020 Jan 31:8:8.
doi: 10.3389/fped.2020.00008. eCollection 2020.

Scurvy: A New Old Cause of Skeletal Pain in Young Children

Christel Chalouhi  1 , Nayla Nicolas  2 , Nancy Vegas  1 , Soraya Matczak  1   3 , Houmam El Jurdi  1 , Nathalie Boddaert  2   3 , Véronique Abadie  1   3
Affiliations
Case Reports

Scurvy: A New Old Cause of Skeletal Pain in Young Children

Christel Chalouhi et al. Front Pediatr. .

"V体育官网入口" Abstract

We report 3 cases of scurvy in children that occurred during a short period (2018) in a general pediatrics unit of a tertiary hospital for children in Paris. All children were around 3 years of age and were admitted for skeletal pain and altered general state, which mimicked infectious or malignant diseases. Their selective diet was not the prominent issue. The diagnosis of scurvy was delayed, after too many unnecessary examinations and medications. Bone imaging findings (X-ray and MRI) were a posteriori considered typical, but lesions were not easily identified as scurvy lesions because scurvy is not well-known by pediatricians and radiologists who should be mindful of this historical diagnosis VSports手机版. .

Keywords: ascorbic acid; scurvy; selective diet; skeletal pain; vitamin C V体育安卓版. .

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Figures (V体育官网)

Figure 1
Figure 1
Left knee radiograph for case I, a 3-year-old boy, demonstrating multiple clear metaphyseal bands in the distal femur (white arrowhead), also defined as “Trummerfeld zone,” and marked white line corresponding to thickened zone of calcification, also named “white line of Frankel.” Irregular and enlarged metaphyseal margin (white arrow), as well as diffuse osteopenia (stars) are also noted.
Figure 2
Figure 2
Bilateral lower leg MRI for case 2, a 3.5-year-old girl: coronal fat-suppressed T2-weighted image revealing bilateral bone-marrow edematous changes of the metaphyseal area (white arrows) of the ankles and knees. Edematous changes were also noted in the distal epiphysis of the femur bilaterally (stars). Whole-body MRI shows multiple similar anomalies in the wrists and shoulders.
Figure 3
Figure 3
Bilateral knee MRI for case 3, a 3-year-old girl: axial fat-suppressed T2-weighted image showing marked bilateral edematous bone-marrow changes within (stars) and around the bone (black arrowheads) associated with bilateral circumferential sub periosteal collections (white arrows) related to bilateral sub-periosteal hematomas.
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References

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