Purpose: This study carried out a meta-analysis to compare immediate surgery (IS) with conservative treatment (CT) of complicated acute appendicitis (CAA) in children. VSports手机版.

Methods: Systematic literature research was performed for relevant studies published from 1969 to date V体育安卓版. Trials of IS compared with CT were included. Outcomes of interest were postoperative morbidity and length of hospital stay (LOS). .

Results: Fifteen trials were studied (1. 243 patients). CT achieved better rates of any complication type (odds ratio [OR] 0. 22, [95% confidence interval (CI): 0. 14, 0. 38], p = 0. 001) and wound infection (OR: 0. 40 [95% CI: 0. 17, 0. 96], p = 0. 041). Neither intraabdominal abscess (OR: 1. 03 [95% CI: 0. 31, 3 V体育ios版. 37], p = 0. 958) nor postoperative ileus (OR: 0. 29 [95% CI: 0. 06, 1. 44], p = 0. 130) was affected by the treatment option. The polled difference in LOS showed a trend for shorter LOS in the IS group (standard mean difference [SMD]: 0. 25 [95% CI: 0. 07, -0. 43], p = 0. 007). .

Conclusions: IS was associated with shorter LOS, while overall complication rates and wound infection declined significantly with CT VSports最新版本. The development of intraabdominal abscess and postoperative ileus was not affected by the treatment of choice. The heterogeneity of most studies depicts the need for randomized controlled trials (RCTs) to discover safe management of CAA in children. .

Level of evidence: III: Type of study: Meta-analysis V体育平台登录. .