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Multicenter Study
. 2018 Aug 10;10(8):1061.
doi: 10.3390/nu10081061.

Mediterranean Diet and Bladder Cancer Risk in Italy

Francesca Bravi  1 , Maria-Eleni Spei  2 , Jerry Polesel  3 , Matteo Di Maso  4   5 , Maurizio Montella  6 , Monica Ferraroni  7 , Diego Serraino  8 , Massimo Libra  9 , Eva Negri  10 , Carlo La Vecchia  11 , Federica Turati  12
Affiliations
Multicenter Study

Mediterranean Diet and Bladder Cancer Risk in Italy (V体育2025版)

Francesca Bravi et al. Nutrients. .

Abstract

Previous studies have reported that Mediterranean diet is inversely related to the risk of several neoplasms; however, limited epidemiological data are available for bladder cancer. Thus, we examined the association between Mediterranean diet and this neoplasm in an Italian multicentric case-control study consisting of 690 bladder cancer cases and 665 controls VSports手机版. We assessed the adherence to the Mediterranean diet via a Mediterranean Diet Score (MDS), which represents the major characteristics of the Mediterranean diet and ranges from 0 to 9 (from minimal to maximal adherence, respectively). We derived odds ratios (ORs) of bladder cancer according to the MDS score from multiple logistic regression models, allowing for major confounding factors. The ORs of bladder cancer were 0. 72 (95% confidence interval, CI, 0. 54⁻0. 98) for MDS of 4⁻5 and 0. 66 (95% CI, 0. 47⁻0. 93) for MDS of 6⁻9 (p for trend = 0. 02) compared to MDS = 0⁻3. Results were similar in strata of sex, age, and education, while the risk appeared somewhat lower in never-smokers and patients with pT1⁻pT4 bladder carcinomas. Among individual components of the MDS, we observed inverse associations for greater consumption of legumes, vegetables, and fish. In our study, which was carried out on an Italian population, the higher adherence to the Mediterranean diet was related to a lower risk of bladder cancer. .

Keywords: Mediterranean diet; bladder cancer; case-control; prevention V体育安卓版. .

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Conflict of interest statement

The authors declare no conflict of interest.

References

    1. Ferlay J., Soerjomataram I., Dikshit R., Eser S., Mathers C., Rebelo M., Parkin D.M., Forman D., Bray F. Cancer incidence and mortality worldwide: Sources, methods and major patterns in globocan 2012. Int. J. Cancer. 2015;136:359–386. doi: 10.1002/ijc.29210. - DOI - PubMed
    1. Van Osch F.H., Jochems S.H., van Schooten F.J., Bryan R.T., Zeegers M.P. Quantified relations between exposure to tobacco smoking and bladder cancer risk: A meta-analysis of 89 observational studies. Int. J. Epidemiol. 2016;45:857–870. doi: 10.1093/ije/dyw044. - DOI - PubMed
    1. Al-Zalabani A.H., Stewart K.F., Wesselius A., Schols A.M., Zeegers M.P. Modifiable risk factors for the prevention of bladder cancer: A systematic review of meta-analyses. Eur. J. Epidemiol. 2016;31:811–851. doi: 10.1007/s10654-016-0138-6. - VSports注册入口 - DOI - PMC - PubMed
    1. Burger M., Catto J.W., Dalbagni G., Grossman H.B., Herr H., Karakiewicz P., Kassouf W., Kiemeney L.A., La Vecchia C., Shariat S., et al. Epidemiology and risk factors of urothelial bladder cancer. Eur. Urol. 2013;63:234–241. doi: 10.1016/j.eururo.2012.07.033. - DOI - PubMed
    1. Kogevinas M., Garcia-Closas M., Trichpoulos D. Urinary bladder cancer. In: Adami H.-O., Hunter D., Trichpoulos D., editors. Cancer Epidemiology. 2nd ed. Oxford Universiy Press; New York, NY, USA: 2008. pp. 573–596.

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