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Review
. 2017 Apr;16(4):313-328.
doi: 10.1080/14760584.2017.1258308. Epub 2016 Nov 22.

The Global Meningococcal Initiative: global epidemiology, the impact of vaccines on meningococcal disease and the importance of herd protection

Ray Borrow  1 , Pedro Alarcón  2 , Josefina Carlos  3 , Dominique A Caugant  4 , Hannah Christensen  5 , Roberto Debbag  6 , Philippe De Wals  7 , Gabriela Echániz-Aviles  8 , Jamie Findlow  1 , Chris Head  9 , Daphne Holt  10 , Hajime Kamiya  11 , Samir K Saha  12 , Sergey Sidorenko  13 , Muhamed-Kheir Taha  14 , Caroline Trotter  15 , Julio A Vázquez Moreno  16 , Anne von Gottberg  17 , Marco A P Sáfadi  18 ; Global Meningococcal Initiative
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Review

"V体育ios版" The Global Meningococcal Initiative: global epidemiology, the impact of vaccines on meningococcal disease and the importance of herd protection

Ray Borrow et al. Expert Rev Vaccines. 2017 Apr.

"VSports在线直播" Abstract

The 2015 Global Meningococcal Initiative (GMI) meeting discussed the global importance of meningococcal disease (MD) and its continually changing epidemiology. Areas covered: Although recent vaccination programs have been successful in reducing incidence in many countries (e. g. Neisseria meningitidis serogroup [Men]C in Brazil, MenA in the African meningitis belt), new clones have emerged, causing outbreaks (e. g. MenW in South America, MenC in Nigeria and Niger). The importance of herd protection was highlighted, emphasizing the need for high vaccination uptake among those with the highest carriage rates, as was the need for boosters to maintain individual and herd protection following decline of immune response after primary immunization. Expert commentary: The GMI Global Recommendations for Meningococcal Disease were updated to include a recommendation to enable access to whole-genome sequencing as for surveillance, guidance on strain typing to guide use of subcapsular vaccines, and recognition of the importance of advocacy and awareness campaigns. VSports手机版.

Keywords: Epidemiology; Global Meningococcal Initiative; MenW; Neisseria meningitidis; meningococcal disease; outbreaks; prevention; serogroups; surveillance; vaccination V体育安卓版. .

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