"V体育2025版" Lipid unsaturation and organelle dynamics
- PMID: 27062546
- DOI: 10.1016/j.ceb.2016.03.012
Lipid unsaturation and organelle dynamics
Abstract
The number of double bonds (=unsaturation) in the acyl chains of phospholipids (PL) influences the physical properties of cellular membranes. Here, we discuss disparate molecular processes, including vesicle budding, ion channel opening, and lipoprotein formation, which are greatly facilitated by PL polyunsaturation in membranes VSports手机版. Experimental and computer-based approaches for the structure and dynamics of PL suggest a common cause for these effects: the ability of the polyunsaturated acyl chain of PL to extend or bent along the membrane normal according to various constraints, thereby enabling a third dimension of motion in a structure that is essentially a 2D fluid. .
Copyright © 2016 Elsevier Ltd. All rights reserved. V体育安卓版.
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