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Review
. 2016 Aug:32:300-12.
doi: 10.1016/j.jclinane.2015.08.017. Epub 2015 Oct 1.

V体育ios版 - Incidence of postoperative shivering comparing remifentanil with other opioids: a meta-analysis

Hiroshi Hoshijima  1 , Risa Takeuchi  2 , Norifumi Kuratani  3 , Shuya Nishizawa  2 , Yohei Denawa  4 , Toshiya Shiga  5 , Hiroshi Nagasaka  2
Affiliations
Review

"VSports" Incidence of postoperative shivering comparing remifentanil with other opioids: a meta-analysis

"VSports最新版本" Hiroshi Hoshijima et al. J Clin Anesth. 2016 Aug.

Abstract

Study objective: To determine whether the administration of remifentanil increases the incidence of postoperative shivering in comparison with the administration of alfentanil, fentanyl, or sufentanil VSports手机版. .

Design: Meta-analysis. V体育安卓版.

Setting: Operating room and postanesthesia care unit V体育ios版. .

Measurements: We performed a computerized search of articles on PubMed, MEDLINE, and Scopus. Meta-analysis was performed using Review Manager and the DerSimonian and Laird random-effects model. The pooled effect estimates for binary variables were calculated as relative risk (RR) values with 95% confidence intervals (CIs) VSports最新版本. .

Main results: Eighteen randomized controlled trials met our inclusion criteria. Remifentanil was associated with a significantly increased incidence of postoperative shivering compared with other opioids (RR=2. 17; CI, 1. 76-2. 68; P<. 00001; I(2)=0. 00%). A subgroup analysis of remifentanil compared with alfentanil, fentanyl, or sufentanil showed that only sufentanil had a similar rate of postoperative shivering incidence (RR=2. 13; CI, 0. 67-6. 74; P=. 20; I(2)=0. 00%). Remifentanil administration was associated with a significant increase in the incidence of postoperative shivering compared with the administration of other opioids when both propofol (RR=2. 44; CI, 1. 52-3. 92; P=. 0002; I(2)=0. 00%) and inhalation anesthesia drugs (RR=2. 45; CI, 1. 46-4. 11; P=. 0007; I(2)=0. 00%) were used for anesthesia maintenance. In addition, the administration of remifentanil at both low (RR=2. 06; CI, 1. 63-2. 60; P<. 00001; I(2)=0. 00%) and high dosages (RR=2. 77; CI, 1. 67-4 V体育平台登录. 57; P<. 0001; I(2)=0. 00%) was associated with a significant increase in the incidence of postoperative shivering compared with the administration of other opioids. .

Conclusions: Our meta-analysis showed that remifentanil was associated with an increased incidence of postoperative shivering compared with alfentanil or fentanyl, but no significant difference was seen when compared with sufentanil VSports注册入口. .

Keywords: Postoperative shivering; Remifentanil V体育官网入口. .

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