Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The . gov means it’s official. Federal government websites often end in . gov or . mil. Before sharing sensitive information, make sure you’re on a federal government site. VSports app下载.

Https

The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely V体育官网. .

. 2014 Feb 25;129(8):837-47.
doi: 10.1161/CIRCULATIONAHA.113.005119. Epub 2013 Dec 17.

Worldwide epidemiology of atrial fibrillation: a Global Burden of Disease 2010 Study

Sumeet S Chugh  1 , Rasmus Havmoeller, Kumar Narayanan, David Singh, Michiel Rienstra, Emelia J Benjamin, Richard F Gillum, Young-Hoon Kim, John H McAnulty Jr, Zhi-Jie Zheng, Mohammad H Forouzanfar, Mohsen Naghavi, George A Mensah, Majid Ezzati, Christopher J L Murray
Affiliations

Worldwide epidemiology of atrial fibrillation: a Global Burden of Disease 2010 Study

"V体育平台登录" Sumeet S Chugh et al. Circulation. .

Abstract

Background: The global burden of atrial fibrillation (AF) is unknown. VSports手机版.

Methods and results: We systematically reviewed population-based studies of AF published from 1980 to 2010 from the 21 Global Burden of Disease regions to estimate global/regional prevalence, incidence, and morbidity and mortality related to AF (DisModMR software). Of 377 potential studies identified, 184 met prespecified eligibility criteria. The estimated number of individuals with AF globally in 2010 was 33. 5 million (20. 9 million men [95% uncertainty interval (UI), 19. 5-22. 2 million] and 12. 6 million women [95% UI, 12. 0-13. 7 million]). Burden associated with AF, measured as disability-adjusted life-years, increased by 18. 8% (95% UI, 15. 8-19. 3) in men and 18. 9% (95% UI, 15. 8-23. 5) in women from 1990 to 2010. In 1990, the estimated age-adjusted prevalence rates of AF (per 100 000 population) were 569. 5 in men (95% UI, 532 V体育安卓版. 8-612. 7) and 359. 9 in women (95% UI, 334. 7-392. 6); the estimated age-adjusted incidence rates were 60. 7 per 100 000 person-years in men (95% UI, 49. 2-78. 5) and 43. 8 in women (95% UI, 35. 9-55. 0). In 2010, the prevalence rates increased to 596. 2 (95% UI, 558. 4-636. 7) in men and 373. 1 (95% UI, 347. 9-402. 2) in women; the incidence rates increased to 77. 5 (95% UI, 65. 2-95. 4) in men and 59. 5 (95% UI, 49. 9-74. 9) in women. Mortality associated with AF was higher in women and increased by 2-fold (95% UI, 2. 0-2. 2) and 1. 9-fold (95% UI, 1. 8-2. 0) in men and women, respectively, from 1990 to 2010. There was evidence of significant regional heterogeneity in AF estimations and availability of population-based data. .

Conclusions: These findings provide evidence of progressive increases in overall burden, incidence, prevalence, and AF-associated mortality between 1990 and 2010, with significant public health implications. Systematic, regional surveillance of AF is required to better direct prevention and treatment strategies V体育ios版. .

Keywords: atrial fibrillation; epidemiology; incidence; prevalence; risk factors, prevention. VSports最新版本.

PubMed Disclaimer

Conflict of interest statement

Conflict of Interest Disclosures: None.

Figures

Figure 1
Figure 1
Conceptual disease model. Flow-chart illustrating the conceptual disease model utilized (DisMod-MR software). The model includes the number of people without the disease (AF in this case), the number of people with the disease, the number of deaths associated with the disease, and the number of deaths from all other causes. The transitions between these states are represented by i: incidence, r: remission, ƒ: case fatality, and m: all other mortality. In the case of AF, remission was assumed to be zero. (Modified from: Barendregt et al. A generic model for the assessment of disease epidemiology: the computational basis of DisMod II. Popul Health Metr. 2003 Apr 14; 1:4. Copyright © 2003 Barendregt et al; licensee BioMed Central Ltd.) (AF- Atrial Fibrillation).
Figure 2
Figure 2
World Map Showing the Age-adjusted Prevalence rates (per 100,000 population) of AF in the 21 Global Burden of Disease (GBD) regions, 2010 (AF- Atrial Fibrillation).
Figure 3
Figure 3
Prevalence of AF: 1990 to 2010. Estimated age-adjusted global prevalence of Atrial Fibrillation (per 100,000 population) for males and females from 1990 to 2010 (AF- Atrial Fibrillation).
Figure 4
Figure 4
Incidence of AF: 1990 & 2010. Estimated age-adjusted global incidence (per 100,000 person years) for males and females for 1990 and 2010. (AF- Atrial Fibrillation)
Figure 5
Figure 5
Mortality Associated with AF: 1990 to 2010. Estimated age-adjusted mortality (per 100,000 population) associated with AF from 1990 to 2010 (AF- Atrial Fibrillation).
Figure 6
Figure 6
Mortality Associated with AF stratified by sex and type of Region (Developed vs. Developing). Mortality associated with AF was higher in males and females in the Developed regions. The significantly higher mortality in females in the Developing regions is responsible for the overall higher AF-related mortality among females compared to males (AF- Atrial Fibrillation).
Figure 7
Figure 7
Proportion of Global deaths Associated with AF in 2010. The map shows color-coded proportions (in percentages) of global deaths in 2010 associated with AF (AF- Atrial Fibrillation)
Figure 8
Figure 8
DALYs Related to AF. Estimated age-adjusted DALYs (per 100,000) related to AF: 1990 to 2010 (AF- Atrial Fibrillation; DALYs- Disability Adjusted Life-Years)
See this image and copyright information in PMC

Comment in

References (VSports在线直播)

    1. Fuster V, Ryden LE, Cannom DS, Crijns HJ, Curtis AB, Ellenbogen KA, Halperin JL, Le Heuzey JY, Kay GN, Lowe JE, Olsson SB, Prystowsky EN, Tamargo JL, Wann S, Smith SC, Jr, Jacobs AK, Adams CD, Anderson JL, Antman EM, Hunt SA, Nishimura R, Ornato JP, Page RL, Riegel B, Priori SG, Blanc JJ, Budaj A, Camm AJ, Dean V, Deckers JW, Despres C, Dickstein K, Lekakis J, McGregor K, Metra M, Morais J, Osterspey A, Zamorano JL. Acc/aha/esc 2006 guidelines for the management of patients with atrial fibrillation: A report of the american college of cardiology/american heart association task force on practice guidelines and the european society of cardiology committee for practice guidelines (writing committee to revise the 2001 guidelines for the management of patients with atrial fibrillation): Developed in collaboration with the european heart rhythm association and the heart rhythm society. Circulation. 2006;114:e257–354. - PubMed
    1. Kannel WB, Wolf PA, Benjamin EJ, Levy D. Prevalence, incidence, prognosis, and predisposing conditions for atrial fibrillation: Population-based estimates. Am J Cardiol. 1998;82:2N–9N. - PubMed
    1. Benjamin EJ, Wolf PA, D’Agostino RB, Silbershatz H, Kannel WB, Levy D. Impact of atrial fibrillation on the risk of death: The framingham heart study. Circulation. 1998;98:946–952. - PubMed (V体育平台登录)
    1. Thrall G, Lane D, Carroll D, Lip GY. Quality of life in patients with atrial fibrillation: A systematic review. Am J Med. 2006;119:448 e441–419. - PubMed
    1. Wang TJ, Larson MG, Levy D, Vasan RS, Leip EP, Wolf PA, D’Agostino RB, Murabito JM, Kannel WB, Benjamin EJ. Temporal relations of atrial fibrillation and congestive heart failure and their joint influence on mortality: The framingham heart study. Circulation. 2003;107:2920–2925. - PubMed

Publication types

MeSH terms