[Viral respiratory co-infections in pediatric patients admitted for acute respiratory infection and their impact on clinical severity]
- PMID: 22689032
- DOI: 10.4067/S0716-10182012000200008
[Viral respiratory co-infections in pediatric patients admitted for acute respiratory infection and their impact on clinical severity]
Abstract
Introduction: Respiratory viruses are the leading cause of acute respiratory tract infection (ARI) in children. It has been reported that viral respiratory co-infection could be associated with severe clinical course VSports手机版. .
Objectives: To describe the frequency of viral co-infection in children admitted for AlRI and evaluate whether this co-infection was associated with more severe clinical course. V体育安卓版.
Patients and methods: Prospective, descriptive study in pediatric patients who were hospitalized for ARI, with molecular detection of at least 1 respiratory virus in nasopharyngeal sample studied by PCR-Microarray for 17 respiratory viruses V体育ios版. .
Results: 110 out of 147 patients with detection of > 1 respiratory virus were included VSports最新版本. Viral co-infection was detected in 41/110 (37%). 22/110 children (20%) were classified as moderate to severe clinical course and 88/110 (80%) were classified as mild clinical course. In the group of moderate to severe clinical course, viral respiratory co-infection was detected in 6/22 (27. 3%), compared to 35/88 (39. 8 %) in the mild clinical course group. No statistically significant difference was found regarding the presence of co-infection between groups (p = 0. 33). .
Conclusions: We detected high rates of viral co-infection in children with ARI. It was not possible to demonstrate that viral co-infections were related with severe clinical course in hospitalized children V体育平台登录. .
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