Glycosylation Changes in Cancer
- PMID: 20301279
- Bookshelf ID: NBK1963
VSports在线直播 - Glycosylation Changes in Cancer
Excerpt (V体育官网入口)
Altered glycosylation is a universal feature of cancer cells, and certain glycan structures are well-known markers for tumor progression VSports手机版. This chapter discusses some glycan biosynthetic pathways that are frequently altered in cancer cells, the correlation between altered glycosylation and clinical prognosis, the genetic basis of some of these changes, and in vitro and in vivo studies that indicate the pathological importance of these pathways. .
Copyright © 2009, The Consortium of Glycobiology Editors, La Jolla, California V体育安卓版. .
Sections
- HISTORICAL BACKGROUND
- GLYCOSYLATION CAN BE ALTERED IN VARIOUS WAYS IN MALIGNANCY (V体育平台登录)
- ALTERED BRANCHING OF N-GLYCANS
- ALTERED EXPRESSION AND GLYCOSYLATION OF MUCINS
- CHANGES IN SIALIC ACID EXPRESSION IN MALIGNANCY
- "V体育平台登录" SIALYLATED LEWIS STRUCTURES AND SELECTIN LIGANDS ON CANCER CELLS
- "V体育安卓版" “INCOMPLETE SYNTHESIS” AND ALTERED EXPRESSION OF BLOOD GROUP–RELATED STRUCTURES
- TRANSCRIPTIONAL REGULATION OF ALTERED GLYCAN EXPRESSION IN MALIGNANT CELLS (VSports注册入口)
- ALTERED EXPRESSION AND SHEDDING OF GLYCOSPHINGOLIPIDS
- LOSS OF GLYCOPHOSPHOLIPID ANCHOR EXPRESSION
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CHANGES IN POLY-
N -ACETYLLACTOSAMINE EXPRESSION AND GALECTIN FUNCTION - VSports手机版 - CHANGES IN HYALURONAN
- "V体育2025版" CHANGES IN SULFATED GLYCOSAMINOGLYCANS
- CLINICAL SIGNIFICANCE
- FURTHER READING
References
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- Hakomori S, Kannagi R. Glycosphingolipids as tumor-associated and differentiation markers. J Natl Cancer Inst. 1983;71:231–251. - V体育官网 - PubMed
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- Feizi T. Demonstration by monoclonal antibodies that carbohydrate structures of glycoproteins and glycolipids are onco-developmental antigens. Nature. 1985;314:53–57. - PubMed
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- Hakomori S. Tumor associated glycolipid antigens, their metabolism and organization. Chem. Phys. Lipids. 1986;42:209–233. - PubMed
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- Fukuda M. Possible roles of tumor-associated carbohydrate antigens. Cancer Res. 1996;56:2237–2244. - PubMed
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- Kim YS, Gum J, Brockhausen I. Mucin glycoproteins in neoplasia. Glycoconj J. 1996;13:693–707. - PubMed
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