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Review
. 2008 Dec;130(6):1079-90.
doi: 10.1007/s00418-008-0527-3. Epub 2008 Oct 25.

VSports注册入口 - Tumor-host interactions: the role of inflammation

Marie-Aude Le Bitoux  1 , Ivan Stamenkovic
Affiliations
Review

Tumor-host interactions: the role of inflammation

Marie-Aude Le Bitoux et al. Histochem Cell Biol. 2008 Dec.

"V体育官网" Abstract

It is well established that interactions between tumor cells and the host tissue stroma play a key role in determining whether and how any given solid malignancy will develop VSports手机版. In most cases, tumor cells hijack stromal cell functions for their own benefit and ultimately dictate the rules of engagement to the host tissue microenvironment. However, the contribution of the different stromal cell components to tumor growth remains to be clarified. Because most solid tumors are accompanied by a local inflammatory response, it has long been thought that inflammation and carcinogenesis are related. If formal proof that cancer can be initiated by inflammation in the absence of exogenous carcinogens is still lacking, there is abundant evidence that the inflammatory response can play a central role in modulating tumor growth and progression. This review will discuss some of the mechanisms whereby inflammation can both enhance and inhibit tumor growth. .

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