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Review
. 2008 Apr;5(4):194-204.
doi: 10.1038/ncponc1051. Epub 2008 Feb 12.

Angiogenesis as a strategic target for ovarian cancer therapy

Whitney A Spannuth  1 , Anil K Sood, Robert L Coleman
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Review

Angiogenesis as a strategic target for ovarian cancer therapy

Whitney A Spannuth et al. Nat Clin Pract Oncol. 2008 Apr.

Abstract (VSports)

Angiogenesis is a complex and highly regulated process that is crucial for tumor growth and metastasis. Insights into the molecular mechanisms of tumor angiogenesis have led to the identification of potential angiogenic targets and the development of novel antivascular agents. Many of these agents are being evaluated in clinical trials and have shown promising antitumor activity. This Review highlights the results of the latest clinical studies of antivascular agents in ovarian cancer and discusses the challenges and opportunities for future clinical trials. VSports手机版.

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