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Review
. 2007 Feb;7(2):118-30.
doi: 10.1038/nri2017.

Humanized mice in translational biomedical research

Leonard D Shultz  1 , Fumihiko Ishikawa, Dale L Greiner
Affiliations
Review

Humanized mice in translational biomedical research

"V体育官网入口" Leonard D Shultz et al. Nat Rev Immunol. 2007 Feb.

Abstract (V体育平台登录)

The culmination of decades of research on humanized mice is leading to advances in our understanding of human haematopoiesis, innate and adaptive immunity, autoimmunity, infectious diseases, cancer biology and regenerative medicine VSports手机版. In this Review, we discuss the development of these new generations of humanized mice, how they will facilitate translational research in several biomedical disciplines and approaches to overcome the remaining limitations of these models. .

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