Racial variation in the prevalence of atrial fibrillation among patients with heart failure: the Epidemiology, Practice, Outcomes, and Costs of Heart Failure (EPOCH) study
- PMID: 15013126
- DOI: 10.1016/j.jacc.2003.09.035
Racial variation in the prevalence of atrial fibrillation among patients with heart failure: the Epidemiology, Practice, Outcomes, and Costs of Heart Failure (EPOCH) study
Abstract
Objectives: This study was designed to determine the association between race and atrial fibrillation (AF) among patients with heart failure (HF). VSports手机版.
Background: Atrial fibrillation is known to complicate HF, but whether its prevalence varies by race, and the reasons why, are not well understood. V体育安卓版.
Methods: We identified adults hospitalized with confirmed HF within a large integrated healthcare delivery system. We obtained information on demographics, comorbidity, vital signs, medications, and left ventricular systolic function status. "Atrial fibrillation" was defined as AF or atrial flutter documented by electrocardiogram or prior physician-assigned diagnoses. We evaluated the independent relationship between race and AF using multivariable logistic regression. V体育ios版.
Results: Among 1,373 HF patients (223 African Americans, 1,150 Caucasians), the prevalence of AF was 36. 9% (95% confidence interval [CI] 34. 3% to 39. 5%). Compared with Caucasians, African Americans were younger (mean age 67 vs. 74 years, p < 0. 001) and more likely to have hypertension (86. 6% vs. 77 VSports最新版本. 7%, p < 0. 01) and prior diagnosed HF (79. 4% vs. 70. 7%, p < 0. 01). African Americans had less prior diagnosed coronary disease, revascularization, hypothyroidism, or valve replacement. Atrial fibrillation was much less prevalent in African Americans (19. 7%) than Caucasians (38. 3%, p < 0. 001). After adjustment for risk factors for AF and other potential confounders, African Americans had 49% lower odds of AF (adjusted odds ratio 0. 51, 95% CI 0. 35 to 0. 76). .
Conclusions: In a contemporary HF cohort, AF was significantly less common among African Americans than among Caucasians V体育平台登录. This variation was not explained by differences in traditional risk factors for AF, HF etiology and severity, and treatment. .
Comment in
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What we're talking about when we talk about race.J Am Coll Cardiol. 2004 Feb 4;43(3):436-7. doi: 10.1016/j.jacc.2003.11.011. J Am Coll Cardiol. 2004. PMID: 15013127 No abstract available.
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