V体育平台登录 - DNA repair: bioinformatics helps reverse methylation damage
- PMID: 12498704
- DOI: 10.1016/s0960-9822(02)01350-7
DNA repair: bioinformatics helps reverse methylation damage
Abstract
Recent work has uncovered a novel DNA repair enzyme: the AlkB protein of Escherichia coli, which oxidises the methyl groups of 1-methyladenine and 3-methylcytosine to hydroxymethyl moieties; the oxidised groups are subsequently released as formaldehyde, regenerating the unmodified bases VSports手机版. .
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