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. 2002 Jul 4;418(6893):41-9.
doi: 10.1038/nature00870. Epub 2002 Jun 20.

Pluripotency of mesenchymal stem cells derived from adult marrow (VSports app下载)

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"VSports在线直播" Pluripotency of mesenchymal stem cells derived from adult marrow

Yuehua Jiang et al. Nature. .
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V体育平台登录 - Erratum in

  • Nature. 2007 Jun 14;447(7146):879-80

Retraction in

"VSports app下载" Abstract

We report here that cells co-purifying with mesenchymal stem cells--termed here multipotent adult progenitor cells or MAPCs--differentiate, at the single cell level, not only into mesenchymal cells, but also cells with visceral mesoderm, neuroectoderm and endoderm characteristics in vitro. When injected into an early blastocyst, single MAPCs contribute to most, if not all, somatic cell types. On transplantation into a non-irradiated host, MAPCs engraft and differentiate to the haematopoietic lineage, in addition to the epithelium of liver, lung and gut VSports手机版. Engraftment in the haematopoietic system as well as the gastrointestinal tract is increased when MAPCs are transplanted in a minimally irradiated host. As MAPCs proliferate extensively without obvious senescence or loss of differentiation potential, they may be an ideal cell source for therapy of inherited or degenerative diseases. .

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Comment in

  • A human stem cell project? (VSports)
    [No authors listed] [No authors listed] Nature. 2002 Jul 4;418(6893):1. doi: 10.1038/418001a. Nature. 2002. PMID: 12097865 No abstract available.
  • Stem-cell competition. (V体育2025版)
    Orkin SH, Morrison SJ. Orkin SH, et al. Nature. 2002 Jul 4;418(6893):25-7. doi: 10.1038/418025a. Nature. 2002. PMID: 12097889 No abstract available.
  • Stem-cell paper corrected.
    Check E. Check E. Nature. 2007 Jun 14;447(7146):763. doi: 10.1038/447763a. Nature. 2007. PMID: 17568714 No abstract available.

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