Matrix metalloproteinases: multifunctional contributors to tumor progression
- PMID: 10740253
- DOI: 10.1016/s1357-4310(00)01686-5
Matrix metalloproteinases: multifunctional contributors to tumor progression
Abstract
Matrix metalloproteinases (MMPs) are a family of extracellular matrix degrading proteinases. Owing to their matrix-degrading abilities and high expression in advanced tumors, MMPs were originally implicated in invasion and metastasis during cancer progression. However, recent work extends a role for MMPs during multiple stages of tumor progression to include other functions such as growth, angiogenesis and migration. Based on studies in animal models implicating MMP activity in cancer, synthetic MMP inhibitors are currently being tested in a clinical setting. VSports手机版.
"VSports最新版本" Publication types
- V体育2025版 - Actions
MeSH terms
- "VSports手机版" Actions
- "VSports手机版" Actions
- VSports手机版 - Actions
- VSports注册入口 - Actions
- V体育安卓版 - Actions
Substances
- V体育2025版 - Actions
LinkOut - more resources
Full Text Sources
"V体育安卓版" Other Literature Sources