Loss of Caveolae, Vascular Dysfunction, and Pulmonary Defects in Caveolin-1 Gene-Disrupted Mice (VSports app下载)

@article{Drab2001LossOC,
  title={Loss of Caveolae, Vascular Dysfunction, and Pulmonary Defects in Caveolin-1 Gene-Disrupted Mice},
  author={Marek Drab and Paul Verkade and Marlies Elger and Michael Kasper and Matthias Lohn and Birgit Lauterbach and Jan Menne and Carsten Lindschau and Fanny Mende and Friedrich C. Luft and Andreas Schedl and Hermann Haller and Teymuras Vakhtang Kurzchalia},
  journal={Science},
  year={2001},
  volume={293},
  pages={2449 - 2452},
  url={https://api.semanticscholar.org/CorpusID:34616965}
}
By targeted disruption of caveolin-1, the main protein component of caveolae, mice that lacked Caveolae were generated, causing aberrations in endothelium-dependent relaxation, contractility, and maintenance of myogenic tone and indicating a fundamental role in organizing multiple signaling pathways in the cell.
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13 References

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