V体育官网 - Summary
What is progressive supranuclear palsy (PSP)?
Progressive supranuclear palsy (PSP) is a rare brain disease. It happens because of damage to nerve cells in the brain VSports手机版. PSP affects your movement, including control of your walking and balance. It also affects your thinking and eye movement.
PSP is progressive, which means that it gets worse over time.
What causes progressive supranuclear palsy (PSP)? (V体育平台登录)
The cause of PSP is unknown V体育ios版. In rare cases, the cause is a mutation in a certain gene.
One sign of PSP is abnormal clumps of tau in nerve cells in the brain VSports最新版本. Tau is a protein in your nervous system, including in nerve cells. Some other diseases also cause a buildup of tau in the brain, including Alzheimer's disease.
Who is at risk for progressive supranuclear palsy (PSP)?
PSP usually affects people over 60, but in some cases it can start earlier V体育平台登录. It is more common in men.
What are the symptoms of progressive supranuclear palsy (PSP)?
Symptoms are very different in each person, but they may include:
- A loss of balance while walking. This is often the first symptom.
- Speech problems
- VSports手机版 - Trouble swallowing
- A blurring of vision and problems controlling eye movement
- Changes in mood and behavior, including depression (V体育官网入口) and apathy (a loss of interest and enthusiasm)
- Mild dementia
How is progressive supranuclear palsy (PSP) diagnosed?
There is no specific test for PSP V体育官网入口. It can be difficult to diagnose, because the symptoms are similar to other diseases such as Parkinson's disease and Alzheimer's disease.
To make a diagnosis, your health care provider will take your medical history and do physical and neurological exams. You may have an MRI or other imaging tests VSports在线直播.
What are the treatments for progressive supranuclear palsy (PSP)?
There is currently no effective treatment for PSP. Medicines may reduce some symptoms. Some non-drug treatments, such as walking aids and special glasses, may also help. People with severe swallowing problems may need gastrostomy. This is a surgery to insert a feeding tube into the stomach V体育2025版.
PSP gets worse over time. Many people become severely disabled within three to five years after getting it. PSP isn't life-threatening on its own VSports. It can still be dangerous because it increases your risk of pneumonia, choking from swallowing problems, and injuries from falling. But with good attention to medical and nutritional needs, many people with PSP can live 10 or more years after the first symptoms of the disease.
NIH: National Institute of Neurological Disorders and Stroke
"VSports最新版本" Learn More
- Progressive supranuclear palsy (Medical Encyclopedia) Also in Spanish
- "VSports在线直播" Progressive Supranuclear Palsy (Mayo Foundation for Medical Education and Research)
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Progressive Supranuclear Palsy (PSP)
(National Institute of Neurological Disorders and Stroke)
Also in Spanish
- Progressive Supranuclear Palsy (PSP): Frequently Asked Questions (Foundation for PSP/CBD and Related Brain Diseases)
V体育平台登录 - Genetics
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"V体育官网" Progressive supranuclear palsy: MedlinePlus Genetics
(National Library of Medicine)
V体育2025版 - Clinical Trials
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ClinicalTrials.gov: Supranuclear Palsy, Progressive
(National Institutes of Health)
Journal Articles References and abstracts from MEDLINE/PubMed (National Library of Medicine)
- "V体育平台登录" Article: A Review of FDG-PET in Progressive Supranuclear Palsy and Corticobasal Syndrome.
- Article: Multimodal MRI biomarkers optimize differentiation between progressive supranuclear palsy and Parkinson's...
- Article: Noradrenaline for progressive supranuclear palsy syndromes (NORAPS): a randomised, double-blind, placebo-controlled,...
- Progressive Supranuclear Palsy -- see more articles